Evidence map›Paper›PMID 37112736›Full record

ArticleVaccines2023

Feeding Spray-Dried Porcine Plasma to Pigs Reduces African Swine Fever Virus Load in Infected Pigs and Delays Virus Transmission-Study 1.

Elena Blázquez, Joan Pujols, Fernando Rodríguez, Joaquim Segalés, Rosa Rosell, Joy Campbell, Javier Polo

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Elena BlázquezIRTA, Centre de Recerca en Sanitat Animal (CReSA), 08193 Barcelona, Spain.
Joan PujolsIRTA, Centre de Recerca en Sanitat Animal (CReSA), 08193 Barcelona, Spain.
Fernando RodríguezIRTA, Centre de Recerca en Sanitat Animal (CReSA), 08193 Barcelona, Spain.ORCID 0000-0001-7361-8408
Joaquim SegalésUnitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), 08193 Barcelona, Spain.ORCID 0000-0002-1539-7261
Rosa RosellUnitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), 08193 Barcelona, Spain.
Joy CampbellAPC LLC, Ankeny, IA 50021, USA.ORCID 0000-0003-2499-3644
Javier PoloAPC Europe, S.L. 08403 Granollers, Spain.ORCID 0000-0003-0990-2230
Universitat Autònoma de Barcelona · ESAPC Europe (Spain) · ESCentre de Recerca en Sanitat Animal · ES

Funding

APC Europe S.L. Support in the form of salaries for authros EB and JPAPC LLC Support in the form of salaries for authors JC and JPSpanish Ministry of Science and Innovation PID2019-107616RB-100
6 · The paper itself

Abstract

The objective of this study was to evaluate the potential benefits of feeding spray-dried porcine plasma (SDPP) to pigs infected with African swine fever virus (ASFV). Two groups of twelve weaned pigs each were fed with CONVENTIONAL or 8% SDPP enriched diets. Two pigs (trojans)/group) were injected intramuscularly with the pandemic ASFV (Georgia 2007/01) and comingled with the rest of the pigs (1:5 trojan:naïve ratio) to simulate a natural route of transmission. Trojans developed ASF and died within the first week after inoculation, but contact pigs did not develop ASF, viremia, or seroconversion. Therefore, three more trojans per group were introduced to optimize the ASFV transmission (1:2 trojan:naïve ratio). Blood, nasal, and rectal swabs were weekly harvested, and at end of the study ASFV-target organs collected. After the second exposure, rectal temperature of conventionally fed contact pigs increased >40.5 °C while fever was delayed in the SDPP contact pigs. Additionally, PCR Ct values in blood, secretions, and tissue samples were significantly lower (

Indexed as

African swine feverASFVchallengenutritional interventionspray-dried porcine plasma

Identifiers

PMID37112736
PMCPMC10142603
OpenAlexW4364376224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.