Evidence map›Paper›PMID 37112602›Full record

ArticleToxics2023

Antitumor Profile of Combined

Sara A Santos, Ricardo G Amaral, Ariel S Graça, Silvana V F Gomes, Fabrício P Santana, Iza B de Oliveira, Luciana N Andrade, Patrícia Severino, Ricardo L C de Albuquerque-Júnior, Sandra L Santos and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Sara A SantosDepartment of Physiology, Federal University of Sergipe, São Cristóvão CEP 49100-000, Brazil.ORCID 0000-0002-1852-107X
Ricardo G AmaralDepartment of Physiology, Federal University of Sergipe, São Cristóvão CEP 49100-000, Brazil.ORCID 0000-0002-9266-6840
Ariel S GraçaDepartment of Physiology, Federal University of Sergipe, São Cristóvão CEP 49100-000, Brazil.
Silvana V F GomesInstitute de Technology and Research (ITP), Tiradentes University, Aracaju CEP 49100-000, Brazil.
Fabrício P SantanaInstitute de Technology and Research (ITP), Tiradentes University, Aracaju CEP 49100-000, Brazil.
Iza B de OliveiraDepartment of Medicine, Campus of Lagarto, Federal University of Sergipe, Lagarto CEP 49400-000, Brazil.ORCID 0000-0002-0869-2203
Luciana N AndradeDepartment of Medicine, Campus of Lagarto, Federal University of Sergipe, Lagarto CEP 49400-000, Brazil.ORCID 0000-0002-5481-4355
Patrícia SeverinoInstitute de Technology and Research (ITP), Tiradentes University, Aracaju CEP 49100-000, Brazil.ORCID 0000-0001-6527-6612
Ricardo L C de Albuquerque-JúniorDepartment of Pathology, Federal University of Santa Catarina, Florianópolis CEP 88040-370, Brazil.ORCID 0000-0003-4444-7632
Sandra L SantosDepartment of Physiology, Federal University of Sergipe, São Cristóvão CEP 49100-000, Brazil.
Eliana B SoutoUCIBIO-Applied Molecular Biosciences Unit, MEDTECH, Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-9737-6017
Adriana A CarvalhoDepartment of Pharmacy, Campus of Lagarto, Federal University of Sergipe, Lagarto CEP 49400-000, Brazil.
Universidade Federal de Sergipe · BRUniversidade do Porto · PTUniversidade Federal de Santa Catarina · BR

Funding

FAPITEC - Foundation for Research Support and Technological Innovation of the State of Sergipe; and CAPES - Coordination for the Improvement of Higher Education Personnel CAPES; FAPITECFCT-Fundação para a Ciência e a Tecnologia, I.P., in the scope of the project UIDP/04378/2020 and UIDB/04378/2020 of the Research Unit on Applied Molecular Biosciences-UCIBIO and the project LA/P/0140/2020 of the Associate Laboratory Institute for Health UIDP/04378/2020 and UIDB/04378/2020
6 · The paper itself

Abstract

Medicinal plants have been commonly associated with chemotherapeutic treatments, as an approach to reduce the toxicological risks of classical anticancer drugs. The objective of this study was to evaluate the effects of combining the antineoplastic drug 5-fluorouracil (5-FU) with

Indexed as

5-fluorouracilantitumorchemotherapyin vivoMatricaria recutitasarcoma 180 model

Identifiers

PMID37112602
PMCPMC10141557
OpenAlexW4365508958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.