Evidence map›Paper›PMID 37112566›Full record

ArticleToxics2023

Present in the Aquatic Environment, Unclear Evidence in Top Predators-The Unknown Effects of Anti-Seizure Medication on Eurasian Otters (

Simon Rohner, Martina Gramer, Ivo Wiesweg, Oliver Scherf-Clavel, Peter Wohlsein, Martin Schmelz, Ursula Siebert, Franziska Richter, Manuela Gernert

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 71% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Simon RohnerInstitute for Terrestrial and Aquatic Wildlife Research, University of Veterinary Medicine Hannover Foundation, 30559 Hannover, Germany.
Martina GramerDepartment of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover Foundation, 30559 Hannover, Germany.
Ivo WieswegDepartment of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover Foundation, 30559 Hannover, Germany.
Oliver Scherf-ClavelFaculty of Chemistry, Aalen University, 73430 Aalen, Germany.ORCID 0000-0002-1967-9231
Peter WohlseinDepartment of Pathology, University of Veterinary Medicine Hannover Foundation, 30559 Hannover, Germany.ORCID 0000-0001-9184-4134
Martin SchmelzAktion Fischotterschutz e.V, Otter-Zentrum Hankensbüttel, 29386 Hankensbüttel, Germany.ORCID 0000-0002-3536-8177
Ursula SiebertInstitute for Terrestrial and Aquatic Wildlife Research, University of Veterinary Medicine Hannover Foundation, 30559 Hannover, Germany.ORCID 0000-0002-2556-3948
Franziska RichterDepartment of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover Foundation, 30559 Hannover, Germany.
Manuela GernertDepartment of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover Foundation, 30559 Hannover, Germany.ORCID 0000-0001-6980-2640
University of Veterinary Medicine Hannover, Foundation · DEHochschule Aalen · DE

Funding

Ministerium für Energiewende, Klimaschutz, Umwelt und Natur Reference AZ: V 5011-063.09-1853/2019
6 · The paper itself

Abstract

Emerging contaminants are produced globally at high rates and often ultimately find their way into the aquatic environment. These include substances contained in anti-seizure medication (ASM), which are currently appearing in surface waters at increasing concentrations in Germany. Unintentional and sublethal, chronic exposure to pharmaceuticals such as ASMs has unknown consequences for aquatic wildlife. Adverse effects of ASMs on the brain development are documented in mammals. Top predators such as Eurasian otters (

Indexed as

anti-seizure medication (ASM)biota monitoringEurasian otterpharmaceuticalspollutiontop predator

Identifiers

PMID37112566
PMCPMC10142713
OpenAlexW4362583680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.