Evidence map›Paper›PMID 37112558›Full record

ArticleToxics2023

From Cohort to Cohort: A Similar Mixture Approach (SMACH) to Evaluate Exposures to a Mixture Leading to Thyroid-Mediated Neurodevelopmental Effects Using NHANES Data.

Maria Sapounidou, Patrik L Andersson, Michelle Leemans, Jean-Baptiste Fini, Barbara Demeneix, Joëlle Rüegg, Carl-Gustaf Bornehag, Chris Gennings

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Maria SapounidouDepartment of Chemistry, Umea University, SE-901 87 Umea, Sweden.ORCID 0000-0001-6097-4657
Patrik L AnderssonDepartment of Chemistry, Umea University, SE-901 87 Umea, Sweden.ORCID 0000-0002-2088-6756
Michelle LeemansUMR 7221, Phyma, CNRS-Muséum National d'Histoire Naturelle, Sorbonne Université, 75005 Paris, France.
Jean-Baptiste FiniUMR 7221, Phyma, CNRS-Muséum National d'Histoire Naturelle, Sorbonne Université, 75005 Paris, France.ORCID 0000-0002-5620-2600
Barbara DemeneixUMR 7221, Phyma, CNRS-Muséum National d'Histoire Naturelle, Sorbonne Université, 75005 Paris, France.
Joëlle RüeggDepartment of Organismal Biology, Environmental Toxicology, Uppsala University, SE-752 36 Uppsala, Sweden.
Carl-Gustaf BornehagFaculty of Health, Science and Technology, Department of Health Sciences, Karlstad University, SE-651 88 Karlstad, Sweden.
Chris GenningsDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-6058-5907
Centre National de la Recherche Scientifique · FRUmeå University · SEIcahn School of Medicine at Mount Sinai · USKarlstad University · SEUppsala University · SE

Funding

Integration of Mixtures Toxicology, Toxicogenomics, and StatisticsT32ES007334 · NIEHS · VIRGINIA COMMONWEALTH UNIVERSITY · PI WHEELER, DAVID CHARLES · 2002 to 2018
$2.5M
Empirical Determination of Sufficiently Similiar Complex MixturesR01ES015276 · NIEHS · VIRGINIA COMMONWEALTH UNIVERSITY · PI GENNINGS, CHRIS · 2007 to 2009
$397k
NIEHS NIH HHS R01 ES015276NIEHS NIH HHS R01ES015276NIEHS NIH HHS T32ES0007334NIEHS NIH HHS T32 ES007334
6 · The paper itself

Abstract

Prenatal exposure to a mixture (MIX N) of eight endocrine-disrupting chemicals has been associated with language delay in children in a Swedish pregnancy cohort. A novel approach was proposed linking this epidemiological association with experimental evidence, where the effect of MIX N on thyroid hormone signaling was assessed using the

Indexed as

causal inferenceendocrine-disrupting chemicalsmixtures risk assessment

Identifiers

PMID37112558
PMCPMC10142960
OpenAlexW4362471509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.