Evidence map›Paper›PMID 37111801›Full record

ArticlePharmaceutics2023

Highly Cytotoxic Copper(II) Mixed-Ligand Quinolinonato Complexes: Pharmacokinetic Properties and Interactions with Drug Metabolizing Cytochromes P450.

Martina Medvedíková, Václav Ranc, Ján Vančo, Zdeněk Trávníček, Pavel Anzenbacher

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Martina MedvedíkováDepartment of Pharmacology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 3, 779 00 Olomouc, Czech Republic.
Václav RancInstitute of Molecular and Translation Medicine, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 779 00 Olomouc, Czech Republic.ORCID 0000-0001-5867-855X
Ján VančoRegional Centre of Advanced Technologies and Materials (RCPTM), Czech Advanced Technology and Research Institute (CATRIN), Palacký University in Olomouc, Šlechtitelů 27, 779 00 Olomouc, Czech Republic.ORCID 0000-0003-3351-1192
Zdeněk TrávníčekRegional Centre of Advanced Technologies and Materials (RCPTM), Czech Advanced Technology and Research Institute (CATRIN), Palacký University in Olomouc, Šlechtitelů 27, 779 00 Olomouc, Czech Republic.ORCID 0000-0002-5890-7874
Pavel AnzenbacherDepartment of Pharmacology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 3, 779 00 Olomouc, Czech Republic.
Institute of Molecular and Translational Medicine · CZRegional Centre of Advanced Technologies and Materials · CZ

Funding

Ministry of Education Youth and Sports CZ.02.1.01/0.0/0.0/16_019/0000754Ministry of Education Youth and Sports LM2018133, EATRIS-CZThe Ministry of Health of the Czech Republic NV19-04-00281
6 · The paper itself

Abstract

The effects of two anticancer active copper(II) mixed-ligand complexes of the type [Cu(qui)(mphen)]Y·H

Indexed as

copper(II) complexescytochrome P450isothermal titration calorimetryquinolinonato derivatives

Identifiers

PMID37111801
PMCPMC10146558
OpenAlexW4366827799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.