ArticlePharmaceutics2023
Hydroxyapatite Thin Films of Marine Origin as Sustainable Candidates for Dental Implants.
Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- Influence of molecular water dynamics on the electrical conductivity of hydrothermally synthesized hydroxyapatite from cuttlefish bone.RSC advances · 2026Article
- Development and Characterization of Biogenic Hydroxyapatite Coatings Derived from Crab Shell Waste on Ti6Al4V Substrates.Materials (Basel, Switzerland) · 2025Article
- Polymeric Composite Thin Films Deposited by Laser Techniques for Antimicrobial Applications-A Short Overview.Polymers · 2025Review
- Hydroxyapatite from Mollusk Shells: Characteristics, Production, and Potential Applications in Dentistry.Dentistry journal · 2024Review
- Synthetic or Natural (Bio-Based) Hydroxyapatite? A Systematic Comparison between Biomimetic Nanostructured Coatings Produced by Ionized Jet Deposition.Nanomaterials (Basel, Switzerland) · 2024Article
- Fabrication Strategies for Bioceramic Scaffolds in Bone Tissue Engineering with Generative Design Applications.Biomimetics (Basel, Switzerland) · 2024Review
- The Effect of Doping on the Electrical and Dielectric Properties of Hydroxyapatite for Medical Applications: From Powders to Thin Films.Materials (Basel, Switzerland) · 2024Review
- Biomimetic Coatings in Implant Dentistry: A Quick Update.Journal of functional biomaterials · 2023Review
- Inhibitory Effect of Adsorption ofInternational journal of molecular sciences · 2023Article
- Editorial: Calcium phosphates of synthetic and natural origin: current status and future challenges.Frontiers in bioengineering and biotechnology · 2023Article
- Hydroxyapatite synthesis and characterization from marine sources: A comparative study.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Novel biomaterials with promising bone regeneration potential, derived from rich, renewable, and cheap sources, are reported. Thus, thin films were synthesized from marine-derived (i.e., from fish bones and seashells) hydroxyapatite (MdHA) by pulsed laser deposition (PLD) technique. Besides the physical-chemical and mechanical investigations, the deposited thin films were also evaluated in vitro using dedicated cytocompatibility and antimicrobial assays. The morphological examination of MdHA films revealed the fabrication of rough surfaces, which were shown to favor good cell adhesion, and furthermore could foster the in-situ anchorage of implants. The strong hydrophilic behavior of the thin films was evidenced by contact angle (CA) measurements, with values in the range of 15-18°. The inferred bonding strength adherence values were superior (i.e., ~49 MPa) to the threshold established by ISO regulation for high-load implant coatings. After immersion in biological fluids, the growth of an apatite-based layer was noted, which indicated the good mineralization capacity of the MdHA films. All PLD films exhibited low cytotoxicity on osteoblast, fibroblast, and epithelial cells. Moreover, a persistent protective effect against bacterial and fungal colonization (i.e., 1- to 3-log reduction of
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.