Evidence map›Paper›PMID 37111718›Full record

ArticlePharmaceutics2023

In Vitro and In Vivo Evaluation of a Bio-Inspired Adhesive for Bone Fixation.

Matthias Schlund, Julien Dartus, Sarah Defrançois, Joël Ferri, Jérôme Delattre, Nicolas Blanchemain, Patrice Woisel, Joël Lyskawa, Feng Chai

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Matthias SchlundUniv. Lille, Inserm, CHU Lille, U1008-Controlled Drug Delivery Systems and Biomaterials, 59000 Lille, France.ORCID 0000-0002-5836-7169
Julien DartusUniv. Lille, Inserm, CHU Lille, U1008-Controlled Drug Delivery Systems and Biomaterials, 59000 Lille, France.
Sarah DefrançoisUniv. Lille, UMET, CNRS, INRAE, Centrale Lille, UMR 8207-UMET, 59000 Lille, France.
Joël FerriUniv. Lille, Inserm, CHU Lille, U1008-Controlled Drug Delivery Systems and Biomaterials, 59000 Lille, France.
Jérôme DelattreUniv. Lille, Univ. Littoral Côte d'Opale, CHU Lille, ULP 4490-MABLab-Adiposité Médullaire er Os, 59000 Lille, France.
Nicolas BlanchemainUniv. Lille, Inserm, CHU Lille, U1008-Controlled Drug Delivery Systems and Biomaterials, 59000 Lille, France.
Patrice WoiselUniv. Lille, UMET, CNRS, INRAE, Centrale Lille, UMR 8207-UMET, 59000 Lille, France.
Joël LyskawaUniv. Lille, UMET, CNRS, INRAE, Centrale Lille, UMR 8207-UMET, 59000 Lille, France.
Feng ChaiUniv. Lille, Inserm, CHU Lille, U1008-Controlled Drug Delivery Systems and Biomaterials, 59000 Lille, France.
Inserm · FRCentre National de la Recherche Scientifique · FRUniversité de Bordeaux · FRUniversité de Lille · FR

Funding

Région Hauts-de-France Start-AIRRUniv. Lille BQI
6 · The paper itself

Abstract

Compared to metallic hardware, an effective bone adhesive can revolutionize the treatment of clinically challenging situations such as comminuted, articular, and pediatric fractures. The present study aims to develop such a bio-inspired bone adhesive, based upon a modified mineral-organic adhesive with tetracalcium phosphate (TTCP) and phosphoserine (OPS) by incorporating nanoparticles of polydopamine (nPDA). The optimal formulation, which was screened using in vitro instrumental tensile adhesion tests, was found to be 50%

Indexed as

animal modelbioresorbable adhesivebone adhesivebone fixationbone glue

Identifiers

PMID37111718
PMCPMC10146643
OpenAlexW4365515720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.