Evidence map›Paper›PMID 37111568›Full record

ArticlePharmaceutics2023

Formulation and Evaluation of Amikacin Sulfate Loaded Dextran Nanoparticles against Human Pathogenic Bacteria.

Rahamat Unissa Syed, Sivakumar S Moni, Muhammad Nawaz, Mohammed Khaled Bin Break, Nasrin E Khalifa, Siddig Ibrahim Abdelwahab, Reham Meshal Alharbi, Raghad Huraid Alfaisal, Bayan Naif Al Basher, Entsar Mohammed Alhaidan

Abstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rahamat Unissa SyedDepartment of Pharmaceutics, College of Pharmacy, University of Ha'il, Hail 81442, Saudi Arabia.
Sivakumar S MoniDepartment of Pharmaceutics, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-4860-0166
Muhammad NawazDepartment of Nano-Medicine Research, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.ORCID 0000-0001-9016-9229
Mohammed Khaled Bin BreakMedical and Diagnostic Research Centre, University of Ha'il, Hail 55473, Saudi Arabia.ORCID 0000-0002-6031-4154
Nasrin E KhalifaDepartment of Pharmaceutics, College of Pharmacy, University of Ha'il, Hail 81442, Saudi Arabia.ORCID 0000-0001-9300-3515
Siddig Ibrahim AbdelwahabMedical Research Center, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-6145-4466
Reham Meshal AlharbiCollege of Pharmacy, University of Ha'il, Hail 81442, Saudi Arabia.
Raghad Huraid AlfaisalCollege of Pharmacy, University of Ha'il, Hail 81442, Saudi Arabia.
Bayan Naif Al BasherCollege of Pharmacy, University of Ha'il, Hail 81442, Saudi Arabia.
Entsar Mohammed AlhaidanCollege of Pharmacy, University of Ha'il, Hail 81442, Saudi Arabia.

Funding

University of Hail MDR 22004
6 · The paper itself

Abstract

Amikacin sulfate-loaded dextran sulfate sodium nanoparticles were formulated, lyophilized (LADNP), and then analyzed. The LADNP had a -20.9 ± 8.35 mV zeta potential, PDI of 0.256, and % PDI of 67.7. The zeta average nano size of LADNP was 317.9 z. d.nm, while the dimension of an individual particle was 259.3 ± 73.52 nm, and nanoparticle conductivity in colloidal solution was 2.36 mS/cm. LADNP has distinct endothermic peaks at temperatures at 165.77 °C, according to differential scanning calorimetry (DSC). The thermogravimetric analysis (TGA) showed the weight loss of LADNP, which was observed as 95% at 210.78 °C. XRD investigation on LADNP exhibited distinct peaks at 2

Indexed as

Amikacinantibacterial effectdextran sulfate sodiumhuman pathogenic bacteriaNanoparticlesphysical characterization

Identifiers

PMID37111568
PMCPMC10145306

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.