ArticlePharmaceutics2023
Impact of Tablet Size and Shape on the Swallowability in Older Adults.
Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Clinicians' Perspectives on the Impact of Different Attributes of Androgen Receptor Pathway Inhibitors on Prostate Cancer Treatment Preferences and Compliance in Mexico.Oncology and therapy · 2026Article
- Tablet Acceptability in Older Outpatients Undergoing Cancer Chemotherapy.Geriatrics (Basel, Switzerland) · 2026Article
- Examining the Use of Pill Swallowing in Dysphagia Assessment: A Survey of Common Practices.Dysphagia · 2026Article
- Article
- Oral Medication Swallowing in Dysphagia: Prevalence of Penetration, Aspiration, Residue, and Epiglottic Morphology Impact-A Retrospective Study.Progress in rehabilitation medicine · 2026Article
- Article
- Research on Enhancing the Solubility and Bioavailability of Canagliflozin Using Spray Drying Techniques with a Quality-by-Design Approach.Pharmaceutics · 2025Article
- Application of a screening tool to understand the medication habits of patients with swallowing difficulty: a prospective observational study.International journal of clinical pharmacy · 2025Observational
- Pill Shape Determines Esophageal Transit Times-A Pill-to-Pill Study.The Laryngoscope · 2025Article
- Selective laser sintering of distinct drug and polymer layers as a novel manufacturing strategy for individually dosed tablets.International journal of pharmaceutics: X · 2025Article
- Effective Therapeutic Strategies to Prevent Frailty and Falls in Community-Dwelling Older Adults.Aging and disease · 2025Review
- From design to 3D printing: A proof-of-concept study for multiple unit particle systems (MUPS) printed by dual extrusion fused filament fabrication.International journal of pharmaceutics: X · 2024Article
- Effect of Liquid Load Level and Binder Type on the Tabletability of Mesoporous Silica Based Liquisolids.AAPS PharmSciTech · 2024Article
- Point Prevalence Survey of Acute Hospital Patients with Difficulty Swallowing Solid Oral Dose Forms.Pharmaceutics · 2024Article
- Factor Analysis of Patients Who Find Tablets or Capsules Difficult to Swallow Due to Their Large Size: Using the Personal Health Record Infrastructure of Electronic Medication Notebooks.Journal of medical Internet research · 2024Article
- Patient Acceptability and Preferences for Solid Oral Dosage Form Drug Product Attributes: A Scoping Review.Patient preference and adherence · 2024Article
- Determination of Gastric Water Emptying in Fasted and Fed State Conditions Using a Compression-Coated Tablet and Salivary Caffeine Kinetics.Pharmaceutics · 2023Article
- Key Considerations during the Transition from the Acute Phase of the COVID-19 Pandemic: A Narrative Review.Vaccines · 2023Review
- Influence of Solid Oral Dosage Form Characteristics on Swallowability, Visual Perception, and Handling in Older Adults.Pharmaceutics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
Older adults represent the major target population for oral medications, due to the high prevalence of multimorbidity. To allow for successful pharmacological treatments, patients need to adhere to their medication and, thus, patient-centric drug products with a high level of acceptability by the end users are needed. However, knowledge on the appropriate size and shape of solid oral dosage forms, as the most commonly used dosage forms in older adults, is still scarce. A randomized intervention study was performed including 52 older adults (65 to 94 years) and 52 young adults (19 to 36 years). Each participant swallowed four coated placebo tablets differing in weight (250 to 1000 mg) and shape (oval, round, oblong) in a blinded manner on three study days. The choice of tablet dimensions allowed for a systematic comparison between different tablet sizes of the same shape, as well as between different tablet shapes. Swallowability was assessed using a questionnaire-based method. All tested tablets were swallowed by ≥80% of adults, independent of age. However, only the 250 mg oval tablet was classified as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.