Evidence map›Paper›PMID 37111490›Full record

ArticlePathogens (Basel, Switzerland)2023

Development of a High-Throughput Urosepsis Mouse Model.

Roman Herout, Sreeparna Vappala, Sarah Hanstock, Igor Moskalev, Ben H Chew, Jayachandran N Kizhakkedathu, Dirk Lange

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Mouse Models of Sepsis.Current protocols · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Roman HeroutThe Stone Centre at Vancouver General Hospital, Department of Urologic Sciences, University of British Columbia, Vancouver, BC V6H 3Z6, Canada.ORCID 0000-0002-9634-2632
Sreeparna VappalaCentre for Blood Research, Life Science Institute, The University of British Columbia, Vancouver, BC V6T 1Z3, Canada.ORCID 0000-0002-1207-4248
Sarah HanstockThe Stone Centre at Vancouver General Hospital, Department of Urologic Sciences, University of British Columbia, Vancouver, BC V6H 3Z6, Canada.ORCID 0000-0003-1744-4401
Igor MoskalevVancouver Prostate Centre, The University of British Columbia, Vancouver, BC V6H 3Z6, Canada.
Ben H ChewThe Stone Centre at Vancouver General Hospital, Department of Urologic Sciences, University of British Columbia, Vancouver, BC V6H 3Z6, Canada.ORCID 0000-0002-5315-0710
Jayachandran N KizhakkedathuCentre for Blood Research, Life Science Institute, The University of British Columbia, Vancouver, BC V6T 1Z3, Canada.ORCID 0000-0001-7688-7574
Dirk LangeThe Stone Centre at Vancouver General Hospital, Department of Urologic Sciences, University of British Columbia, Vancouver, BC V6H 3Z6, Canada.
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Murine sepsis models are typically polymicrobial, and are associated with high mortality. We aimed to develop a high-throughput murine model that mimics a slow-paced, monomicrobial sepsis originating from the urinary tract. A total of 23 male C57Bl/6 mice underwent percutaneous insertion of a 4 mm catheter into the bladder using an ultrasound-guided method, previously developed by our group. The following day,

Indexed as

catheter-associated urinary tract infectionmouse modelurosepsis

Identifiers

PMID37111490
PMCPMC10143079
OpenAlexW4366090741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.