Evidence map›Paper›PMID 37111451›Full record

ArticlePathogens (Basel, Switzerland)2023

Consistent Measurement of Parasite-Specific Antigen Levels in Sera of Patients with Neurocysticercosis Using Two Different Monoclonal Antibody (mAb)-Based Enzyme-Linked Immunosorbent Assays.

Yesenia Castillo, Luz M Toribio, Carolina Guzman, Gianfranco Arroyo, Cindy Espinoza, Herbert Saavedra, Javier A Bustos, Pierre Dorny, Seth E O'Neal, Hector H Garcia and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Yesenia CastilloCenter for Global Health, Universidad Peruana Cayetano Heredia, Lima 15202, Peru.
Luz M ToribioCenter for Global Health, Universidad Peruana Cayetano Heredia, Lima 15202, Peru.
Carolina GuzmanCenter for Global Health, Universidad Peruana Cayetano Heredia, Lima 15202, Peru.
Gianfranco ArroyoCenter for Global Health, Universidad Peruana Cayetano Heredia, Lima 15202, Peru.ORCID 0000-0001-8743-5012
Cindy EspinozaCenter for Global Health, Universidad Peruana Cayetano Heredia, Lima 15202, Peru.
Herbert SaavedraCysticercosis Unit, National Institute of Neurological Sciences, Lima 15030, Peru.
Javier A BustosCenter for Global Health, Universidad Peruana Cayetano Heredia, Lima 15202, Peru.
Pierre DornyDepartment of Biomedical Sciences, Institute of Tropical Medicine, 2060 Antwerp, Belgium.ORCID 0000-0001-5381-7987
Seth E O'NealCenter for Global Health, Universidad Peruana Cayetano Heredia, Lima 15202, Peru.
Hector H GarciaCenter for Global Health, Universidad Peruana Cayetano Heredia, Lima 15202, Peru.
Cysticercosis Working Group in Peru
Universidad Peruana Cayetano Heredia · PEBloomberg (United States) · USInstituto Nacional de Ciencias NeurológicasInstituut voor Tropische Geneeskunde · BEPortland State University · US

Funding

Training in Parasitic Diseases and Central Nervous System Infections in Peru.D43TW001140 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI GARCIA, HECTOR HUGO, GILMAN, ROBERT H · 1999 to 2025
$5.7M
Urine Screening for Early Detection of Subarachnoid NeurocysticercosisR01NS103623 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI GARCIA, HECTOR HUGO, O'NEAL, SETH E · 2018 to 2023
$3.0M
Scientific CoreU19AI129909 · NIAID · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI GARCIA, HECTOR HUGO · 2017 to 2021
$2.8M
FIC NIH HHS D43 TW001140NIAID NIH HHS U19 AI129909
6 · The paper itself

Abstract

Monoclonal antibody (mAb)-based enzyme-linked immunosorbent assay (ELISA) is a complementary diagnosis technique for neurocysticercosis (NCC), which detects circulating parasite antigen (Ag) indicative of viable infection and Ag levels that correlate well with the parasite burden. In this study, we compared the performance of two Ag-ELISA techniques for the detection of NCC. We assessed the agreement between our in-house TsW8/TsW5 Ag-ELISA and the widely used B158/B60 Ag-ELISA for measuring

Indexed as

Ag-ELISAagreementmonoclonal antibodiesneurocysticercosisTaenia solium

Identifiers

PMID37111451
PMCPMC10143799
OpenAlexW4362667570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.