Evidence map›Paper›PMID 37111431›Full record

ArticlePathogens (Basel, Switzerland)2023

Novel Experimental Mouse Model to Study Malaria-Associated Acute Kidney Injury.

Johanna Bensalel, Alexandra Roberts, Kiara Hernandez, Angelica Pina, Winifred Prempeh, Blessing V Babalola, Pablo Cannata, Alberto Lazaro, Julio Gallego-Delgado

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Pathology of Severe Malaria.Pathogens (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Johanna BensalelDepartment of Biological Sciences, Bronx, Lehman College, The City University of New York, New York, NY 10468, USA.ORCID 0009-0005-8218-0504
Alexandra RobertsDepartment of Biological Sciences, Bronx, Lehman College, The City University of New York, New York, NY 10468, USA.
Kiara HernandezDepartment of Biological Sciences, Bronx, Lehman College, The City University of New York, New York, NY 10468, USA.
Angelica PinaDepartment of Biological Sciences, Bronx, Lehman College, The City University of New York, New York, NY 10468, USA.
Winifred PrempehDepartment of Biological Sciences, Bronx, Lehman College, The City University of New York, New York, NY 10468, USA.
Blessing V BabalolaDepartment of Biological Sciences, Bronx, Lehman College, The City University of New York, New York, NY 10468, USA.
Pablo CannataDepartment of Pathology, IIS-Fundación Jiménez Díaz, School of Medicine, Universidad Autónoma de Madrid, 28040 Madrid, Spain.
Alberto LazaroRenal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0002-1095-679X
Julio Gallego-DelgadoDepartment of Biological Sciences, Bronx, Lehman College, The City University of New York, New York, NY 10468, USA.ORCID 0000-0002-8914-7740

Funding

New strategies to study malaria-induced acute kidney injurySC2GM144168 · NIGMS · HERBERT H. LEHMAN COLLEGE · PI GALLEGO-DELGADO, JULIO · 2021 to 2023
$468k
NIGMS NIH HHS DSP SC2GM 144168NIGMS NIH HHS SC2 GM144168NIGMS NIH HHS SC2GM144168
6 · The paper itself

Abstract

The impact of malaria-associated acute kidney injury (MAKI), one of the strongest predictors of death in children with severe malaria (SM), has been largely underestimated and research in this area has been neglected. Consequently, a standard experimental mouse model to research this pathology is still lacking. The purpose of this study was to develop an in vivo model that resembles the pathology in MAKI patients. In this study, unilateral nephrectomies were performed on wild-type mice prior to infection with

Indexed as

acute kidney injuryAKIMAKImalariarenal impairmentsevere malariasevere malaria mouse model

Identifiers

PMID37111431
PMCPMC10141210

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.