Evidence map›Paper›PMID 37111388›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

The First Anti-Snakebite and Hepatoprotective Characterization of a Trypsin Kunitz-like Inhibitor (EcTI) from the Plant

Caroline R C Costa, Mariana N Belchor, Airam Roggero, Laila L Moraes, Ricardo Samelo, Isabelly Annunciato, Camila R Bonturi, Maria L V Oliva, Sergio F Sousa, Marcos A de Oliveira and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Caroline R C CostaCenter of Natural and Human Sciences, Federal University of ABC (UFABC), Santo André 09210-580, SP, Brazil.
Mariana N BelchorCenter of Natural and Human Sciences, Federal University of ABC (UFABC), Santo André 09210-580, SP, Brazil.
Airam RoggeroBiosciences Institute of Paulista Coast Campus (IB/CLP), University of São Paulo State (UNESP), São Vicente 11330-900, SP, Brazil.ORCID 0000-0003-4546-8013
Laila L MoraesBiosciences Institute of Paulista Coast Campus (IB/CLP), University of São Paulo State (UNESP), São Vicente 11330-900, SP, Brazil.
Ricardo SameloBiosciences Institute of Paulista Coast Campus (IB/CLP), University of São Paulo State (UNESP), São Vicente 11330-900, SP, Brazil.
Isabelly AnnunciatoBiosciences Institute of Paulista Coast Campus (IB/CLP), University of São Paulo State (UNESP), São Vicente 11330-900, SP, Brazil.ORCID 0000-0001-7884-6768
Camila R BonturiNational Institute of Pharmacology (INFAR), Federal University of São Paulo (UNIFESP), São Paulo 04044-020, SP, Brazil.ORCID 0000-0001-9324-8424
Maria L V OlivaNational Institute of Pharmacology (INFAR), Federal University of São Paulo (UNIFESP), São Paulo 04044-020, SP, Brazil.ORCID 0000-0001-7346-6328
Sergio F SousaUnit of Applied Biomolecular Sciences (UCIBIO), REQUIMTE-BioSIM-Medicine Faculty, Porto University, 4050-345 Porto, Portugal.ORCID 0000-0002-6560-5284
Marcos A de OliveiraCenter of Natural and Human Sciences, Federal University of ABC (UFABC), Santo André 09210-580, SP, Brazil.
Marcos H ToyamaCenter of Natural and Human Sciences, Federal University of ABC (UFABC), Santo André 09210-580, SP, Brazil.
Universidade de São Paulo · BRUniversidade Federal de São Paulo · BRUniversidade do Porto · PT

Funding

National Council for Scientific and Technological Development 309271/2022-3São Paulo Research Foundation 2006/52801-3São Paulo Research Foundation 2017/20291-0
6 · The paper itself

Abstract

Snake venom serine protease (SVSP) interferes with the regulation and control of important biological reactions in homeostasis and can be classified as an activator of the fibrinolytic system and platelet aggregation. Our group has recently isolated a new serine protease from

Indexed as

Cdtsp-2Crotalus durissus terrificusKunitz-type inhibitorserine protease

Identifiers

PMID37111388
PMCPMC10145096
OpenAlexW4366775342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.