Evidence map›Paper›PMID 37111311›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

TEAD Inhibitors Sensitize KRAS

Salvina Laura Tammaccaro, Philippe Prigent, Jean-Christophe Le Bail, Odette Dos-Santos, Laurent Dassencourt, Myriam Eskandar, Armelle Buzy, Olivier Venier, Jean-Claude Guillemot, Yaligara Veeranagouda and 14 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. "Undruggable KRAS": druggable after all.Genes & development · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 1 institution in 1 country.

Salvina Laura TammaccaroOncology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Philippe PrigentOncology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Jean-Christophe Le BailOncology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Odette Dos-SantosOncology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Laurent DassencourtOncology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Myriam EskandarOncology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Armelle BuzyBio Structure and Biophysics, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Olivier VenierSmall Molecules Medicinal Chemistry, Sanofi R&D, 91380 Chilly-Mazarin, France.
Jean-Claude GuillemotGenomics and Proteomics, Translational Sciences, Sanofi R&D, 91380 Chilly-Mazarin, France.
Yaligara VeeranagoudaGenomics and Proteomics, Translational Sciences, Sanofi R&D, 91380 Chilly-Mazarin, France.
Michel DidierGenomics and Proteomics, Translational Sciences, Sanofi R&D, 91380 Chilly-Mazarin, France.
Emmanuel SpanakisPrecision Oncology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Tokuwa KannoPrecision Oncology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Matteo CesaroniPrecision Oncology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Stephane MathieuMolecular & Digital Histopathology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Luc CanardMolecular & Digital Histopathology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Alhassan CasseMolecular & Digital Histopathology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Fanny WindenbergerNon-Clinical Efficacy and Safety, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Loreley CalvetPharmacology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Laurence NobletPharmacology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Sukhvinder SidhuPharmacology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Laurent DebusscheOncology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Jurgen MollOncology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Iris ValtingojerOncology, Sanofi R&D, 94400 Vitry-sur-Seine, France.
Sanofi (France) · FR

Funding

Sanofi (France) NO GRANT NUMBER
6 · The paper itself

Abstract

KRAS

Indexed as

cell cycle arrestKRASG12CNSCLCresistanceYAP1-TEAD

Identifiers

PMID37111311
PMCPMC10142471
OpenAlexW4362668006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.