Evidence map›Paper›PMID 37111298›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Discovery of Small-Molecule Antagonists of Orexin 1/2 Receptors from Traditional Chinese Medicinal Plants with a Hypnotic Effect.

Jia He, Jing Fang, Yuxin Wang, Chengyu Ge, Shao Liu, Yueping Jiang

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jia HeDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, China.
Jing FangDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, China.
Yuxin WangCollege of Pharmacy, Dali University, Dali 671000, China.
Chengyu GeDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, China.
Shao LiuDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0002-0576-8698
Yueping JiangDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0002-5820-0123
Central South University · CNDali University · CN

Funding

Hunan Traditional Chinese Medicine Scientific Research Project 2021195Nature Sciences Foundation of Hunan Province 2021JJ80084; 2022JJ80115
6 · The paper itself

Abstract

Insomnia is an important public health problem. The currently available treatments for insomnia can cause some adverse effects. Orexin receptors 1 (OX

Indexed as

in-home ligand libraryneferineorexin receptorsscreening and verificationtraditional Chinese medicine (TCM)

Identifiers

PMID37111298
PMCPMC10146837
OpenAlexW4362634941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.