Evidence map›Paper›PMID 37111245›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

ABT-333 (Dasabuvir) Increases Action Potential Duration and Provokes Early Afterdepolarizations in Canine Left Ventricular Cells via Inhibition of I

Zsigmond Máté Kovács, József Óvári, Csaba Dienes, János Magyar, Tamás Bányász, Péter P Nánási, Balázs Horváth, Adam Feher, Zoltan Varga, Norbert Szentandrássy

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Zsigmond Máté KovácsDepartment of Physiology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
József ÓváriDepartment of Physiology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Csaba DienesDepartment of Physiology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
János MagyarDepartment of Physiology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Tamás BányászDepartment of Physiology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0003-3894-0738
Péter P NánásiDepartment of Physiology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Balázs HorváthDepartment of Physiology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0003-2562-8446
Adam FeherDoctoral School of Molecular Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-3638-5067
Zoltan VargaDepartment of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0003-1892-6840
Norbert SzentandrássyDepartment of Physiology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0003-0197-9567
University of Debrecen · HU

Funding

National Research Development and Innovation Office K138090, K142764, FK128116, K132906New National Excellence Program of the Ministry for Innovation and Technology ÚNKP-22-3-II-DE-112, ÚNKP-22-3-II-DE-38Thematic Excellence Program of the Ministry for Innovation and Technology in Hungary TKP-2020-NKA-04
6 · The paper itself

Abstract

ABT-333 (dasabuvir) is an antiviral agent used in hepatitis C treatment. The molecule, similarly to some inhibitors of hERG channels, responsible for the delayed rectifier potassium current (I

Indexed as

ABT-333action potentialcaninecardiomyocytedasabuvirhepatitis C virushERGIKrItolong QT syndrome

Identifiers

PMID37111245
PMCPMC10143825
OpenAlexW4361007555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.