Evidence map›Paper›PMID 37110679›Full record

ArticleMolecules (Basel, Switzerland)2023

Simultaneous Quantification of Trehalose and Trehalose 6-Phosphate by Hydrophilic Interaction Chromatography/Electrospray Accurate Mass Spectrometry with Application in Non-Targeted Metabolomics.

Ye Tao, Yannick Rossez, Clovis Bortolus, Luminita Duma, Faustine Dubar, Franck Merlier

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Identification of Chemical Constituents inMolecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ye TaoSorbonne Universités, Université de Technologie de Compiègne, Génie Enzymatique et Cellulaire (GEC), UMR-CNRS 7025, CS 60319, 60203 Compiègne Cedex, France.
Yannick RossezSorbonne Universités, Université de Technologie de Compiègne, Génie Enzymatique et Cellulaire (GEC), UMR-CNRS 7025, CS 60319, 60203 Compiègne Cedex, France.ORCID 0000-0001-5435-1373
Clovis BortolusINSERM U1285, Université de Lille, CHU de Lille, UMR CNRS 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, 59000 Lille, France.
Luminita DumaSorbonne Universités, Université de Technologie de Compiègne, Génie Enzymatique et Cellulaire (GEC), UMR-CNRS 7025, CS 60319, 60203 Compiègne Cedex, France.ORCID 0000-0002-9072-6803
Faustine DubarINSERM U1285, Université de Lille, CHU de Lille, UMR CNRS 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, 59000 Lille, France.ORCID 0000-0002-0233-7067
Franck MerlierSorbonne Universités, Université de Technologie de Compiègne, Génie Enzymatique et Cellulaire (GEC), UMR-CNRS 7025, CS 60319, 60203 Compiègne Cedex, France.ORCID 0000-0002-8895-8357

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-resolution mass spectrometry (HRMS) was coupled with ultra-high-performance liquid chromatography (UHPLC) to simultaneously quantify trehalose and trehalose 6-phosphate without derivatization or sample preparation. The use of full scan mode and exact mass analysis also makes it possible to carry out metabolomic analyses as well as semi-quantification. In addition, the use of different clusters in negative mode makes it possible to compensate for deficiencies in linearity and inerrant saturation at time-of-flight detectors. The method has been approved and validated for different matrices, yeasts, and bacteria, and has shown differentiation between bacteria as a function of growth temperatures.

Indexed as

MetabolomicsTrehaloseChromatography, High Pressure LiquidHydrophobic and Hydrophilic InteractionsMass SpectrometryPhosphatesPhosphatesTrehalosehigh resolution time-of-flight MSHILICsugarsugar phosphatetrehalosetrehalose 6-phosphate

Identifiers

PMID37110679
PMCPMC10145281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.