Evidence map›Paper›PMID 37110635›Full record

ArticleMolecules (Basel, Switzerland)2023

Synthesis and Characterization of Carvedilol-Etched Halloysite Nanotubes Composites with Enhanced Drug Solubility and Dissolution Rate.

Lauretta Maggi, Claudia Urru, Valeria Friuli, Chiara Ferrara, Debora Maria Conti, Giovanna Bruni, Doretta Capsoni

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lauretta MaggiDepartment of Drug Sciences, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-1408-8846
Claudia UrruDepartment of Chemistry, Physical Chemistry Section & C.S.G.I. (Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase), University of Pavia, 27100 Pavia, Italy.
Valeria FriuliDepartment of Drug Sciences, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy.
Chiara FerraraDepartment of Materials Science, University of Milano-Bicocca, Via Cozzi 55, 20125 Milano, Italy.ORCID 0000-0002-5834-8646
Debora Maria ContiDepartment of Chemistry, Physical Chemistry Section & C.S.G.I. (Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase), University of Pavia, 27100 Pavia, Italy.
Giovanna BruniDepartment of Chemistry, Physical Chemistry Section & C.S.G.I. (Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase), University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-1958-2998
Doretta CapsoniDepartment of Chemistry, Physical Chemistry Section & C.S.G.I. (Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase), University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-1064-7196
University of Pavia · ITUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carvedilol is a poorly water-soluble drug employed to treat chronic heart failure. In this study, we synthesize new carvedilol-etched halloysite nanotubes (HNTs) composites to enhance solubility and dissolution rate. The simple and feasible impregnation method is used for carvedilol loading (30-37% weight). Both the etched HNTs (acidic HCl and H

Indexed as

NanotubesCarvedilolClaySolubilitySpectroscopy, Fourier Transform InfraredCarvedilolClaycarvediloldissolution testsdrug–nanoclay compositeshalloysite nanotubessolid-state NMR

Identifiers

PMID37110635
PMCPMC10142978
OpenAlexW4365448762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.