Evidence map›Paper›PMID 37110335›Full record

ArticleMicroorganisms2023

Molecular In-Depth on the Epidemiological Expansion of SARS-CoV-2 XBB.1.5.

Fabio Scarpa, Ilenia Azzena, Chiara Locci, Marco Casu, Pier Luigi Fiori, Alessandra Ciccozzi, Silvia Angeletti, Elena Imperia, Marta Giovanetti, Antonello Maruotti and 7 more

Abstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Integrative Genome-Based Survey of the SARS-CoV-2 Omicron XBB.1.16 Variant.International journal of molecular sciences · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Fabio ScarpaDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-3501-714X
Ilenia AzzenaDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Chiara LocciDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Marco CasuDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-5042-4851
Pier Luigi FioriDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0001-6190-612X
Alessandra CiccozziUnit of Medical Statistics and Molecular Epidemiology, University Campus Bio-Medico of Rome, 00128 Rome, Italy.
Silvia AngelettiUnit of Clinical Laboratory Science, Department of Medicine and Surgery, University Campus Bio-Medico of Rome, 00128 Rome, Italy.
Elena ImperiaUnit of Medical Statistics and Molecular Epidemiology, University Campus Bio-Medico of Rome, 00128 Rome, Italy.
Marta GiovanettiInstituto Rene Rachou, Fundação Oswaldo Cruz, Belo Horizonte 30190-009, Minas Gerais, Brazil.ORCID 0000-0002-5849-7326
Antonello MaruottiDepartment GEPLI, Libera Università Ss Maria Assunta, 00193 Rome, Italy.ORCID 0000-0001-8377-9950
Alessandra BorsettiNational HIV/AIDS Research Center, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-5401-135X
Roberto CaudaUOC Malattie Infettive, Infectious Disease Department, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Antonio CassoneCenter of Genomic, Genetic and Biology, 53100 Siena, Italy.
Allegra ViaDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza Università di Roma, 00185 Rome, Italy.
Stefano PascarellaDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza Università di Roma, 00185 Rome, Italy.ORCID 0000-0002-6822-4022
Daria SannaDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-3058-4663
Massimo CiccozziUnit of Medical Statistics and Molecular Epidemiology, University Campus Bio-Medico of Rome, 00128 Rome, Italy.ORCID 0000-0003-3866-9239

Funding

CRP-ICGEB RESEARCH GRANT 2020 Project CRP/BRA20-03 (Marta Giovanetti) contract CRP/20/03, Oswaldo Cruz FoundationFONDAZIONE DI SARDEGNA bando 2022-2023 for the Dipartimento di Scienze Biomediche - UNISS (to Fabio Scarpa and Daria Sanna) NAPON "Ricerca e Innovazione" 2014-2020 (Marta Giovanetti) NASapienza (Stefano Pascarella) RP12117A7670A1E8
6 · The paper itself

Abstract

Since the beginning of the pandemic, the generation of new variants periodically recurs. The XBB.1.5 SARS-CoV-2 variant is one of the most recent. This research was aimed at verifying the potential hazard of this new subvariant. To achieve this objective, we performed a genome-based integrative approach, integrating results from genetic variability/phylodynamics with structural and immunoinformatic analyses to obtain as comprehensive a viewpoint as possible. The Bayesian Skyline Plot (BSP) shows that the viral population size reached the plateau phase on 24 November 2022, and the number of lineages peaked at the same time. The evolutionary rate is relatively low, amounting to 6.9 × 10

Indexed as

COVID-18molecular epidemiologypandemicsphylogenomicsSARS-CoV-2XBB.1.5

Identifiers

PMID37110335
PMCPMC10142263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.