Evidence map›Paper›PMID 37110180›Full record

ArticleMetabolites2023

Oral Exposure to Epoxiconazole Disturbed the Gut Micro-Environment and Metabolic Profiling in Male Mice.

You Weng, Ting Xu, Caihong Wang, Yuanxiang Jin

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

You WengCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China.
Ting XuCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China.
Caihong WangCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China.
Yuanxiang JinCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China.ORCID 0000-0003-4135-553X
Zhejiang University of Technology · CN

Funding

National Natural Science Foundation of China 42277279Natural Science Foundation of Zhejiang Province LZ20B070002
6 · The paper itself

Abstract

Epoxiconazole (EPX), a triazole fungicide, is widely used in agriculture to control pests and diseases. High residual and occupational exposure to EPX increases health risks, and evidence of potential harm to mammals remains to be added. In the present study, 6-week-old male mice were exposed to 10 and 50 mg/kg bw EPX for 28 days. The results showed that EPX significantly increased the liver weights. EPX also decreased the mucus secretion of the colon and altered intestinal barrier function in mice including a reduced expression of some genes (

Indexed as

epoxiconazolegut microbiotaintestinal barriermetabolomemice

Identifiers

PMID37110180
PMCPMC10144212
OpenAlexW4362670499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.