Evidence map›Paper›PMID 37110178›Full record

ArticleMetabolites2023

High-Fat-Diet Suppressed Ketone Body Utilization for Lipogenic Pathway in Brown Adipose Tissues.

Masahiro Yamasaki, Shinya Hasegawa, Shotaro Ozaki, Masahiko Imai, Daisuke Saito, Noriko Takahashi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Masahiro YamasakiDepartment of Health Chemistry, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan.ORCID 0000-0002-5296-4974
Shinya HasegawaDepartment of Health Chemistry, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan.ORCID 0000-0003-2731-8097
Shotaro OzakiDepartment of Health Chemistry, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan.
Masahiko ImaiDepartment of Health Chemistry, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan.
Daisuke SaitoDepartment of Health Chemistry, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan.
Noriko TakahashiDepartment of Health Chemistry, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan.
Hoshi University · JP

Funding

Japan Society for the Promotion of Science JP15K08048
6 · The paper itself

Abstract

Brown adipose tissue (BAT) consumes excess lipids and produces lipid metabolites as ketone bodies. These ketone bodies are then recycled for lipogenesis by the enzyme acetoacetyl-CoA synthetase (AACS). Previously, we found that a high-fat diet (HFD) upregulated AACS expression in white adipose tissue. In this study, we investigated the effects of diet-induced obesity on AACS in BAT. When 4-week-old ddY mice were fed a HFD or high-sucrose diet (HSD) for 12 weeks, a significant decrease in

Indexed as

acetoacetyl-CoA synthetasebrown adipose tissueketone bodylipid metabolismobesity

Identifiers

PMID37110178
PMCPMC10145826
OpenAlexW4362670277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.