Evidence map›Paper›PMID 37109758›Full record

ReviewMedicina (Kaunas, Lithuania)2023

Assessing Critical Flicker Fusion Frequency: Which Confounders? A Narrative Review.

Thomas Muth, Jochen D Schipke, Anne-Kathrin Brebeck, Sven Dreyer

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Critical flicker fusion frequency: confounders and caveats.European journal of applied physiology · 2026
    Article
  3. Article
  4. Article
  5. The Effects of Light on Vertebrate Welfare: A Review.Animals : an open access journal from MDPI · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas MuthInstitute of Occupational, Social, Environmental Medicine, Faculty of Medicine, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany.
Jochen D SchipkeResearch Group Experimental Surgery, University Hospital Düsseldorf, 40225 Düsseldorf, Germany.ORCID 0000-0002-1747-5657
Anne-Kathrin BrebeckArtemis Augenklinik, 60314 Frankfurt, Germany.ORCID 0000-0003-1848-0316
Sven DreyerHyperbaric Oxygen Therapy, University Hospital Düsseldorf, 40225 Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The critical flicker fusion frequency (cFFF) refers to the frequency at which a regularly recurring change of light stimuli is perceived as steady. The cFFF threshold is often assessed in clinics to evaluate the temporal characteristics of the visual system, making it a common test for eye diseases. Additionally, it serves as a helpful diagnostic tool for various neurological and internal diseases. In the field of diving/hyperbaric medicine, cFFF has been utilized to determine alertness and cognitive functions. Changes in the cFFF threshold have been linked to the influence of increased respiratory gas partial pressures, although there exist inconsistent results regarding this effect. Moreover, the use of flicker devices has produced mixed outcomes in previous studies. This narrative review aims to explore confounding factors that may affect the accuracy of cFFF threshold measurements, particularly in open-field studies. We identify five broad categories of such factors, including (1) participant characteristics, (2) optical factors, (3) smoking/drug use, (4) environmental aspects, and (5) breathing gases and partial pressures. We also discuss the application of cFFF measurements in the field of diving and hyperbaric medicine. In addition, we provide recommendations for interpreting changes in the cFFF threshold and how they are reported in research studies.

Indexed as

DivingFlicker FusionCognitionHumansSmokingalertnesscognitioncritical flicker fusion frequencydivinghyperbaric medicineneurological diseasesvisual system

Identifiers

PMID37109758
PMCPMC10141404

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.