Evidence map›Paper›PMID 37109652›Full record

ArticleMedicina (Kaunas, Lithuania)2023

Bacterial Production of Recombinant Coagulation Factor VIII Domains.

Saima Bashar, Hee-Jin Jeong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Saima BasharIndustry-Academia Cooperation Foundation, Hongik University, 2639 Sejong-ro, Sejong-si 30016, Republic of Korea.
Hee-Jin JeongDepartment of Biological and Chemical Engineering, Hongik University, 2639 Sejong-ro, Sejong-si 30016, Republic of Korea.
Hongik University · KR

Funding

National Research Foundation of Korea (NRF) grants funded by the Korean Government 2020R1I1A307411712 and 2021H1D3A2A02096525Social Welfare Corporation Korea Hemophilia Foundation 2020 Hemophilia Research grant (2020-01)
6 · The paper itself

Abstract

Factor VIII (F8) is a blood coagulation protein prearranged in six domains, and its deficiency causes hemophilia A. To fashion functional F8 therapeutics, development of a recombinant F8 (rF8) domain is essential not only for F8 substitution, but also to decipher the F8-related mechanisms. In this study, we generated Glutathione S-transferase (GST)-conjugated recombinant A2 and A3 domains of F8 using

Indexed as

Factor VIIIHemophilia AAntibodiesBlood CoagulationEscherichia coliHumansRecombinant ProteinsAntibodiesFactor VIIIRecombinant Proteinscoagulation factor disordersfactor VIIIhemophilia Arecombinant protein

Identifiers

PMID37109652
PMCPMC10143837
OpenAlexW4362578075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.