ArticleLife (Basel, Switzerland)2023
Straightforward Creation of Possibly Prebiotic Complex Mixtures of Thiol-Rich Peptides.
Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Messy Chemistry and the Emergence of Life.Life (Basel, Switzerland) · 2026Article
- Amino acid analogues provide multiple plausible pathways to prebiotic peptides.Journal of the Royal Society, Interface · 2024Review
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Authors and funding
4 authors.
Funding
Abstract
At the origin of life, extremely diverse mixtures of oligomers and polymers could be obtained from relatively simple molecular bricks. Here, we present an example of the polymerization of two amidonitriles derived from cysteine, Cys-Ala-CN and Cys-Met-CN. The thiol function in a molecule adds onto the nitrile group of another one, allowing efficient condensation reactions and making available an extensive range of polymers containing amide bonds and/or five-membered heterocycles, namely thiazolines. Macrocycles were also identified, the biggest one containing sixteen residues (cyclo(Cys-Met)
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Registered trials
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