Evidence map›Paper›PMID 37109477›Full record

ReviewLife (Basel, Switzerland)2023

Phytochemicals as Invaluable Sources of Potent Antimicrobial Agents to Combat Antibiotic Resistance.

Ragi Jadimurthy, Swamy Jagadish, Siddaiah Chandra Nayak, Sumana Kumar, Chakrabhavi Dhananjaya Mohan, Kanchugarakoppal S Rangappa

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Natural product based approaches to overcomeFrontiers in antibiotics · 2026
    Review
  9. Review
  10. Article
  11. Release Profile and Antibacterial Activity ofBioengineering (Basel, Switzerland) · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Essential oils of Eugenia spp. (myrtaceae) show in vitro antibacterial activity against Staphylococcus aureus isolates from bovine mastitis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ragi JadimurthyDepartment of Studies in Molecular Biology, University of Mysore, Manasagangotri, Mysore 570006, India.
Swamy JagadishDepartment of Studies in Molecular Biology, University of Mysore, Manasagangotri, Mysore 570006, India.
Siddaiah Chandra NayakDepartment of Studies in Biotechnology, University of Mysore, Manasagangotri, Mysore 570006, India.
Sumana KumarDepartment of Microbiology, Faculty of Life Sciences, JSS Academy of Higher Education and Research, Mysore 570015, India.
Chakrabhavi Dhananjaya MohanDepartment of Studies in Molecular Biology, University of Mysore, Manasagangotri, Mysore 570006, India.
Kanchugarakoppal S RangappaInstitution of Excellence, Vijnana Bhavan, University of Mysore, Manasagangotri, Mysore 570006, India.
University of Mysore · INJSS Academy of Higher Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants have been used for therapeutic purposes against various human ailments for several centuries. Plant-derived natural compounds have been implemented in clinics against microbial diseases. Unfortunately, the emergence of antimicrobial resistance has significantly reduced the efficacy of existing standard antimicrobials. The World Health Organization (WHO) has declared antimicrobial resistance as one of the top 10 global public health threats facing humanity. Therefore, it is the need of the hour to discover new antimicrobial agents against drug-resistant pathogens. In the present article, we have discussed the importance of plant metabolites in the context of their medicinal applications and elaborated on their mechanism of antimicrobial action against human pathogens. The WHO has categorized some drug-resistant bacteria and fungi as critical and high priority based on the need to develope new drugs, and we have considered the plant metabolites that target these bacteria and fungi. We have also emphasized the role of phytochemicals that target deadly viruses such as COVID-19, Ebola, and dengue. Additionally, we have also elaborated on the synergetic effect of plant-derived compounds with standard antimicrobials against clinically important microbes. Overall, this article provides an overview of the importance of considering phytogenous compounds in the development of antimicrobial compounds as therapeutic agents against drug-resistant microbes.

Indexed as

antibacterialantifungalantiviralnatural compoundsphytocompounds

Identifiers

PMID37109477
PMCPMC10145550
OpenAlexW4362617416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.