Evidence map›Paper›PMID 37109457›Full record

ArticleLife (Basel, Switzerland)2023

Bone Disease in Long-Term Lung Transplant Survivors.

Giorgia Grassi, Elisa Cairoli, Lucrezia Maria Silvana Gentile, Iacopo Chiodini, Marta Zampogna, Alberto Ghielmetti, Letizia Corinna Morlacchi, Valeria Rossetti, Lorenzo Rosso, Ilaria Righi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Giorgia GrassiUnit of Endocrinology, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-7236-0713
Elisa CairoliUnit for Bone Metabolism Diseases and Diabetes, Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, 20122 Milan, Italy.ORCID 0000-0001-8767-6385
Lucrezia Maria Silvana GentileDepartment of Clinical Sciences and Community Health, University of Milan, 20123 Milan, Italy.
Iacopo ChiodiniUnit of Endocrinology, Ospedale Niguarda Cà Granda, 20162 Milan, Italy.ORCID 0000-0001-7594-3300
Marta ZampognaDepartment of Clinical Sciences and Community Health, University of Milan, 20123 Milan, Italy.
Alberto GhielmettiDepartment of Clinical Sciences and Community Health, University of Milan, 20123 Milan, Italy.
Letizia Corinna MorlacchiRespiratory Unit, Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-4661-6471
Valeria RossettiRespiratory Unit, Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-3814-7484
Lorenzo RossoDepartment of Pathophysiology and Transplantation, University of Milan, 20123 Milan, Italy.ORCID 0000-0002-9809-7140
Ilaria RighiThoracic Surgery and Lung Transplant Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Mario NosottiDepartment of Pathophysiology and Transplantation, University of Milan, 20123 Milan, Italy.
Maura ArosioUnit of Endocrinology, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0003-3988-3616
Francesco BlasiRespiratory Unit, Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Cristina Eller VainicherUnit of Endocrinology, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
University of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITIRCCS Istituto Auxologico Italiano · IT

Funding

Italian Ministry of Health Ricerca Corrente 2021
6 · The paper itself

Abstract

backgroundDuring the first two years after lung transplantation (LTx), the incidence of fragility fractures (FX) is estimated to be 15-50% and it is lower in patients with cystic fibrosis (CF) as compared with other end-stage lung diseases (nCF). The aim of our study is to compare the skeletal outcomes, after the first 2 years post-LTx, in long-term survivors with CF and nCF. MATERIALS AND

methodsWe evaluated the FX rate, the changes in bone mineral density (BMD) and trabecular bone score (TBS) in 68 patients (38 CF and 30 nCF) who underwent LTx in our center and with a follow-up after LTx longer than 5 years (7.3 ± 2.0 years).

resultsAfter the second year post-LTx: (i) the FX rate was lower than during the first two years post-LTx (4.4 vs. 20.6%,

conclusionsAfter the second year post-LTx, the skeletal complications become less frequent and have similar incidence in patients with CF and nCF.

Indexed as

cystic fibrosislung transplantationtrabecular bone scorevertebral fractures

Identifiers

PMID37109457
PMCPMC10146054
OpenAlexW4362586188

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.