Evidence map›Paper›PMID 37109454›Full record

ReviewLife (Basel, Switzerland)2023

Analytical Determination of Heavy Metals in Human Seminal Plasma-A Systematic Review.

Andrea López-Botella, Raquel Sánchez, Raiza Paul, Jon Aizpurua, María José Gómez-Torres, José-Luis Todolí-Torró

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Cu-doped InRSC advances · 2025
    Article
  2. Article
  3. Electrochemical Detection of CdNanomaterials (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andrea López-BotellaBiotechnology Department, Faculty of Sciences, University of Alicante, Carretera San Vicente del Raspeig s/n, 03690 Alicante, Spain.ORCID 0000-0001-9931-826X
Raquel SánchezDepartment of Analytical Chemistry, Nutrition and Food Sciences, University of Alicante, Carretera San Vicente del Raspeig s/n, 03690 Alicante, Spain.ORCID 0000-0003-0283-6103
Raiza PauliGLS, Av. de Ansaldo, 12, 03540 Alicante, Spain.
Jon AizpuruaIVF Spain, Reproductive Medicine, 03540 Alicante, Spain.
María José Gómez-TorresBiotechnology Department, Faculty of Sciences, University of Alicante, Carretera San Vicente del Raspeig s/n, 03690 Alicante, Spain.ORCID 0000-0003-2384-8154
José-Luis Todolí-TorróDepartment of Analytical Chemistry, Nutrition and Food Sciences, University of Alicante, Carretera San Vicente del Raspeig s/n, 03690 Alicante, Spain.ORCID 0000-0002-9151-7050
University of Alicante · ESClínica IVI Alicante · ES

Funding

Ministerio de Ciencia e Innovación PID2021-127566NB-I00
6 · The paper itself

Abstract

Infertility is a growing concerning health problem affecting around 15% of couples worldwide. Conventional semen parameters have limited accuracy for male infertility potential determination. Current advances in the understanding of male infertility indicate that environmental and occupational exposure to chemical contaminants are important etiological factors leading to infertility problems. In this context, some heavy metals (HMs) can be considered as endocrine-disrupting compounds (EDCs), thus altering the seminal quality. This systematic review aims to summarize the key points to detect and quantify HMs in human seminal plasma (SP) and the involved analytical tools. Our results showed that that for HM quantification, atomic absorption spectroscopy (AAS) and inductively coupled plasma (ICP) were the most employed techniques while Zn, Cd, Pb, and Cr were the analytes most often detected. Fast, reliable, and sensitive quantification of EDCs in SP could be important for the development of accurate diagnostic and preventive strategies to address male infertility towards providing personalized therapy.

Indexed as

endocrine-disrupting compoundsenvironmental factorsheavy metalslifestyle factorsmale infertilityseminal biomarkersseminal plasma

Identifiers

PMID37109454
PMCPMC10145970
OpenAlexW4362591224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.