Evidence map›Paper›PMID 37109430›Full record

ArticleLife (Basel, Switzerland)2023

Ulceration and a White Lesion of the Tongue in a Male HIV Positive Patient: A Journey on the Avenue of Differential Diagnoses in Search of a Solution.

Manuela Arbune, Monica-Daniela Padurariu-Covit, Elena Niculet, Iulia Chiscop, Anca-Adriana Arbune, Alin-Laurențiu Tatu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Manuela ArbuneClinical Medical Department, Medicine and Pharmacy Faculty, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.
Monica-Daniela Padurariu-CovitThe School for Doctoral Studies in Biomedical Sciences, "Dunarea de Jos" University of Galați, 800008 Galati, Romania.ORCID 0000-0002-4237-2297
Elena NiculetMultidisciplinary Integrated Center of Dermatological Interface Research (MIC-DIR), "Dunarea de Jos" University, 800010 Galati, Romania.ORCID 0000-0001-9249-5247
Iulia ChiscopOral and Maxillofacial Surgery Department, Emergency County Hospital "Sf. Apostol Andrei", 800578 Galati, Romania.
Anca-Adriana ArbuneMultidisciplinary Integrated Center of Dermatological Interface Research (MIC-DIR), "Dunarea de Jos" University, 800010 Galati, Romania.
Alin-Laurențiu TatuClinical Medical Department, Medicine and Pharmacy Faculty, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.ORCID 0000-0003-4290-7068
Clinical Emergency Hospital Bucharest · RO"Dunarea de Jos" University of Galati · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral lesions are early indicator of immunosuppression, leading to HIV new diagnoses. The type of oral lesions can reveal opportunistic diseases that are correlated with the severity of immune depletion. Highly active antiretroviral therapy decreases the incidence of opportunistic oral infections, whereas a large variety of lesions are frequently experienced in people with HIV. Overlapping pathogenic mechanisms and multiple contributing etiologies are related to unusual, atypical oral lesions that are challenging in the clinical practice. We present a rare case of eosinophilic granuloma of the tongue in an older male HIV patient with severe immunosuppression due to the failure of antiretroviral treatment. Differential diagnoses considered squamous carcinoma, lymphoma, viral, fungal or bacterial infections and autoimmune disorders, as well as the influence of HIV immune disfunctions or the influence of cannabidiol use. The histopathologic and immunohistochemistry examination clarified the inflammatory reactive benign substrate of the lesion, although future survey of the oral lesions is essential.

Indexed as

cannabinoidseosinophilic granulomaHIVtonguewhite oral lesion

Identifiers

PMID37109430
PMCPMC10147043
OpenAlexW4361293891

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.