Evidence map›Paper›PMID 37109324›Full record

ArticleJournal of clinical medicine2023

Impact of the Family and Household Environment on Pediatric Atopic Dermatitis in Japan.

Hidehisa Saeki, Yukihiro Ohya, Hisakatsu Nawata, Kazuhiko Arima, Miho Inukai, Ana B Rossi, Gaelle Bego-Le-Bagousse

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Next-Generation Probiotics in Allergy Therapy: Scientific Evidence and Clinical Applications.Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2026
    Review
  3. Article
  4. Prevention of Atopic Dermatitis: What Are We Missing?Allergy, asthma & immunology research · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Hidehisa SaekiDepartment of Dermatology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan.
Yukihiro OhyaAllergy Center, National Center for Child Health and Development, Setagaya-ku, Tokyo 157-8535, Japan.ORCID 0000-0002-1560-3942
Hisakatsu NawataImmunology Medical, Sanofi K.K., Shinjuku-ku, Tokyo 163-1488, Japan.
Kazuhiko ArimaImmunology Medical, Sanofi K.K., Shinjuku-ku, Tokyo 163-1488, Japan.ORCID 0000-0002-0607-8787
Miho InukaiMarket Access, Sanofi K.K., Shinjuku-ku, Tokyo 163-1488, Japan.
Ana B RossiSanofi, Cambridge, MA 02139, USA.
Gaelle Bego-Le-BagousseSanofi, Chilly-Mazarin, 91380 Paris, France.
Sanofi (Japan) · JPNational Center For Child Health and Development · JPNippon Medical School · JPSanofi (France) · FRSanofi (United States) · US

Funding

Sanofi and Regeneron Pharmaceuticals, Inc. N/A
6 · The paper itself

Abstract

Pediatric atopic dermatitis (AD) can negatively impact the family quality of life (QoL). We report data from the real-world Epidemiology of Children with Atopic Dermatitis Reporting on their Experience (EPI-CARE) study in Japanese pediatric patients, focusing on disease impact on family QoL. Children and adolescents aged 6 months to <18 years completed an online survey between September 2018-December 2019. The impact of disease severity on family QoL and its effect on parents' time were assessed using the dermatitis family impact (DFI) questionnaire. The impact of a family history of allergic conditions, current residency, second-hand smoke exposure, and household pets on AD prevalence and severity was also assessed. Family QoL decreased as AD severity increased, particularly in families with children aged <6 years; but had the greatest impact on sleep and tiredness in families with children aged <12 years. Parents spent at least 4.6 h/week caring for children <6 years, including those with mild symptoms. Most children (>80%) had a family history of allergic conditions; AD prevalence was increased in those exposed to second-hand smoke or household pets. This study demonstrated that pediatric AD in Japanese individuals has negative impacts on family QoL and that family and household environments can influence pediatric AD prevalence.

Indexed as

atopicchilddermatitisfamilyquality of life

Identifiers

PMID37109324
PMCPMC10145633
OpenAlexW4366590531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.