Evidence map›Paper›PMID 37109302›Full record

ArticleJournal of clinical medicine2023

Characterization of Hypomagnesemia in Alcoholic Hepatitis Patients and Its Association with Liver Injury and Severity Markers.

Evan J Winrich, Harsh Tiwari, Khushboo S Gala, Amor J Royer, Dipendra Parajuli, Vatsalya Vatsalya

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Evan J WinrichDepartment of Medicine, University of Louisville, Louisville, KY 40202, USA.
Harsh TiwariDepartment of Medicine, University of Louisville, Louisville, KY 40202, USA.
Khushboo S GalaDepartment of Medicine, University of Louisville, Louisville, KY 40202, USA.
Amor J RoyerDepartment of Medicine, University of Louisville, Louisville, KY 40202, USA.
Dipendra ParajuliDepartment of Medicine, University of Louisville, Louisville, KY 40202, USA.
Vatsalya VatsalyaDepartment of Medicine, University of Louisville, Louisville, KY 40202, USA.ORCID 0000-0001-6764-6891
University of Louisville · US

Funding

Role of oxidized linoleic acid metabolites in the pathogenesis of alcoholic liver diseaseP20GM113226 · NIGMS · UNIVERSITY OF LOUISVILLE · PI HOOD, JOSHUA L. · 2016 to 2025
$24.1M
The Role of Nutrition in the Development/Progression of Alcohol-Induced Organ InjuryP50AA024337 · NIAAA · UNIVERSITY OF LOUISVILLE · PI CRAIG J. MCCLAIN · 2016 to 2026
$17.9M
Mechanisms of Probiotics in Alcoholic Liver DiseaseR01AA023190 · NIAAA · UNIVERSITY OF LOUISVILLE · PI FENG, WENKE · 2015 to 2024
$3.5M
Intramural NIH HHS Z99 AA999999NIAAA NIH HHS AA999999 (VV)NIAAA NIH HHS K23-AA023190 (VV)NIAAA NIH HHS P50 AA024337NIAAA NIH HHS R01 AA023190NIGMS NIH HHS P20 GM113226
6 · The paper itself

Abstract

introductionHypomagnesemia has been documented in alcohol-associated liver disease (ALD). This study aims to characterize hypomagnesemia in alcoholic hepatitis (AH) patients and identify its response with liver injury and severity markers. MATERIALS AND

methodsA total of 49 male and female AH patients with an age range of 27-66 years were enrolled in this study. Patients were grouped by MELD: MiAH (mild AH < 12 [

resultsSMg was deficient in each group; the lowest in the MoAH patients. The true positivity of SMg values were at a good performance level when compared between severe and non-severe AH patients (AUROC: 0.695,

conclusionsThis study demonstrates the utility of SMg levels to identify AH patients who may have progressed to severe status. The extent of magnesium response in AH patients also corresponded significantly with the prognosis of liver disease. Physicians suspecting AH in patients with recent heavy drinking may use SMg as an indicator to guide further testing, referrals, or treatment.

Indexed as

ABICalcohol-associated hepatitisalcohol-associated liver diseasehypomagnesemiamagnesiumMELDmortalitysevere AH

Identifiers

PMID37109302
PMCPMC10142006
OpenAlexW4366584828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.