Evidence map›Paper›PMID 37109260›Full record

ArticleJournal of clinical medicine2023

Impact of Age and Sex Interaction on Post-Acute Sequelae of COVID-19: An Italian Cohort Study on Adults and Children.

Matteo Puntoni, Susanna Esposito, Laura Patrizi, Chiara Maria Palo, Michela Deolmi, Giovanni Autore, Valentina Fainardi, Caterina Caminiti, On Behalf Of The University Hospital Of Parma Long-Covid Research Team

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Matteo PuntoniClinical & Epidemiological Research Unit, University Hospital of Parma, 43125 Parma, Italy.ORCID 0000-0002-7908-0626
Susanna EspositoPediatric Clinic, Department of Medicine and Surgery, University of Parma, University Hospital of Parma, 43125 Parma, Italy.
Laura PatriziClinical & Epidemiological Research Unit, University Hospital of Parma, 43125 Parma, Italy.ORCID 0000-0002-7315-169X
Chiara Maria PaloClinical & Epidemiological Research Unit, University Hospital of Parma, 43125 Parma, Italy.
Michela DeolmiPediatric Clinic, Department of Medicine and Surgery, University of Parma, University Hospital of Parma, 43125 Parma, Italy.ORCID 0000-0001-5877-025X
Giovanni AutorePediatric Clinic, Department of Medicine and Surgery, University of Parma, University Hospital of Parma, 43125 Parma, Italy.ORCID 0000-0002-5895-8313
Valentina FainardiPediatric Clinic, Department of Medicine and Surgery, University of Parma, University Hospital of Parma, 43125 Parma, Italy.
Caterina CaminitiClinical & Epidemiological Research Unit, University Hospital of Parma, 43125 Parma, Italy.ORCID 0000-0002-3196-2435
On Behalf Of The University Hospital Of Parma Long-Covid Research Team
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identifying factors predisposing individuals to post-acute sequelae of COVID-19 (PASC) would allow for the timely treatment of those vulnerable. Attention on the role of sex and age is growing, but published studies have shown mixed results. Our objective was to estimate the effect modification of age on sex as a risk factor for PASC. We analyzed data from two longitudinal prospective cohort studies on adult and pediatric subjects positive to SARS-CoV-2 infection that were enrolled between May 2021 and September 2022. Age classes (≤5, 6-11, 12-50, >50 years) were based on the potential role of sex hormones on inflammatory/immune and autoimmune processes. A total of 452 adults and 925 children were analyzed: 46% were female and 42% were adults. After a median follow-up of 7.8 months (IQR: 5.0 to 9.0), 62% of children and 85% of adults reported at least one symptom. Sex and age alone were not significantly associated to PASC, but their interaction was statistically significant (

Indexed as

ageCOVID-19post-acute sequelaesex hormones

Identifiers

PMID37109260
PMCPMC10144783
OpenAlexW4366284227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.