Evidence map›Paper›PMID 37109244›Full record

ArticleJournal of clinical medicine2023

Are There Maternal Deaths Related to Hemorrhagic Stroke Due to Hypertensive Disorder of Pregnancy That Could Be Potentially Preventable by Tight Hypertension Management in Antepartum? A Retrospective Study from the Maternal Death Exploratory Committee in Japan.

Hiroaki Tanaka, Junichi Hasegawa, Shinji Katsuragi, Kayo Tanaka, Tatsuya Arakaki, Masamitsu Nakamura, Eijiro Hayata, Masahiko Nakata, Akihiko Sekizawa, Isamu Ishiwata and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Postpartum and interpregnancy care of women with a history of hypertensive disorders of pregnancy.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Hiroaki TanakaDepartment of Obstetrics and Gynecology, Mie University School of Medicine, Edobashi 2-174, Tsu 514-8507, Mie, Japan.ORCID 0000-0002-1760-691X
Junichi HasegawaJapan Maternal Death Exploratory Committee, Ichigayahachimantyou 14, Shinjuku, Tokyo 162-0844, Japan.ORCID 0000-0002-5789-1022
Shinji KatsuragiJapan Maternal Death Exploratory Committee, Ichigayahachimantyou 14, Shinjuku, Tokyo 162-0844, Japan.
Kayo TanakaJapan Maternal Death Exploratory Committee, Ichigayahachimantyou 14, Shinjuku, Tokyo 162-0844, Japan.
Tatsuya ArakakiJapan Maternal Death Exploratory Committee, Ichigayahachimantyou 14, Shinjuku, Tokyo 162-0844, Japan.
Masamitsu NakamuraJapan Maternal Death Exploratory Committee, Ichigayahachimantyou 14, Shinjuku, Tokyo 162-0844, Japan.
Eijiro HayataJapan Maternal Death Exploratory Committee, Ichigayahachimantyou 14, Shinjuku, Tokyo 162-0844, Japan.
Masahiko NakataJapan Maternal Death Exploratory Committee, Ichigayahachimantyou 14, Shinjuku, Tokyo 162-0844, Japan.
Akihiko SekizawaJapan Maternal Death Exploratory Committee, Ichigayahachimantyou 14, Shinjuku, Tokyo 162-0844, Japan.ORCID 0000-0003-2249-1333
Isamu IshiwataJapan Maternal Death Exploratory Committee, Ichigayahachimantyou 14, Shinjuku, Tokyo 162-0844, Japan.
Tomoaki IkedaDepartment of Obstetrics and Gynecology, Mie University School of Medicine, Edobashi 2-174, Tsu 514-8507, Mie, Japan.
Mie University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnlike Europe and the United States, Japan has seen numerous maternal deaths from hemorrhagic strokes related to hypertensive disorders of pregnancy (HDP). This study retrospectively analyzed deaths associated with HDP-related hemorrhagic stroke in Japan to determine the number of deaths that may have been prevented with blood pressure control during pregnancy.

methodsThis study included maternal deaths related to hemorrhagic stroke cases. The proportion of patients without proteinuria whose blood pressure exceeded 140/90 mmHg between 14+0 and 33+6 weeks of gestation were determined. Lastly, the application of tight antihypertensive management was evaluated.

resultsAmong 34 HDP-related maternal deaths, 4 cases involved patients without proteinuria whose blood pressures exceeded 140/90 mmHg between 14+0 and 33+6 weeks of gestation. These included two chronic hypertension and two gestational hypertension cases. None of the patients received antihypertensive agents, and their blood pressures were managed leniently.

conclusionAmong HDP-related hemorrhagic stroke deaths in Japan, only a few cases of maternal death could have been prevented with tight blood pressure management, as described in the CHIPS randomized controlled trial. Therefore, to prevent HDP-related hemorrhagic stroke in Japan, new preventive strategies during pregnancy should be established.

Indexed as

CHIPS randomized controlled trialhemorrhagic strokematernal death

Identifiers

PMID37109244
PMCPMC10140809
OpenAlexW4366089049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.