ArticleJournal of clinical medicine2023
Spinal Cord Stimulation Prevents Autonomic Dysreflexia in Individuals with Spinal Cord Injury: A Case Series.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06587841 (Noninvasive Spinal Cord Neuromodulation to Improve Lower Urinary Tract Function After Spinal Cord Injury in Ukrainian War Veterans), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Noninvasive Spinal Cord Neuromodulation to Improve Lower Urinary Tract Function After Spinal Cord Injury in Ukrainian War Veterans
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Spinal cord stimulation to manage autonomic dysfunction after spinal cord injury: a systematic review.Frontiers in human neuroscience · 2026Pooled it
- Spinal cord neuromodulation for autonomic recovery following spinal cord injury: a scoping review.Journal of neuroengineering and rehabilitation · 2026Article
- Article
- Evaluation and management of autonomic functions in patients with spinal cord injury: A scoping review.The journal of spinal cord medicine · 2026Article
- Effective management of orthostatic hypotension in a patient with complete spinal cord injury using a portable transcutaneous spinal cord stimulation device: A case report.The journal of spinal cord medicine · 2026Article
- Electroceuticals for Paralympic Athletes: A Fair Play and Classification Concern?Sports medicine (Auckland, N.Z.) · 2026Review
- Article
- Short-Term Repeated Transcutaneous Spinal Cord Stimulation Yields Sustained Orthostatic Benefits in Chronic Cervical SCI: A Case Study.Journal of clinical medicine · 2025Article
- Multi-system benefits of non-invasive spinal cord stimulation following cervical spinal cord injury: a case study.Bioelectronic medicine · 2025Article
- Cardiovascular safety of transcutaneous spinal cord stimulation in cervical spinal cord injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Special Issue-Spinal Cord Injuries: Advances in Rehabilitation.Journal of clinical medicine · 2024Article
- Autonomic dysreflexia in urological practice: pathophysiology, prevention and treatment considerations.World journal of urology · 2024Review
- Epidural Spinal Cord Stimulation for Spinal Cord Injury in Humans: A Systematic Review.Journal of clinical medicine · 2024Review
- Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation-Mapping for a Blood Pressure Response: A Case Series.Neurotrauma reports · 2024Article
- Ergogenic effects of spinal cord stimulation on exercise performance following spinal cord injury.Frontiers in neuroscience · 2024Article
- Transcutaneous Spinal Cord Stimulation to Stabilize Seated Systolic Blood Pressure in Persons With Chronic Spinal Cord Injury: Protocol Development.Neurotrauma reports · 2023Article
- Cardiovascular Responses to Bladder and Bowel Distension after Human Spinal Cord Injury.Neurotrauma reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Spinal cord injury (SCI) results in severe cardiovascular dysfunction due to the disruption of supraspinal control. Autonomic dysreflexia (AD), an uncontrolled rise in blood pressure in response to peripheral stimuli including common bowel routine, digital anorectal stimulation (DARS), reduces the quality of life, and increases morbidity and mortality. Recently, spinal cord stimulation (SCS) has emerged as a potential intervention to mitigate unstable blood pressure following SCI. The objective of this case series was to test the real-time effect of epidural SCS (eSCS) at the lumbosacral spinal cord, the most common implant location, on mitigating AD in individuals with SCI. We recruited three individuals with cervical and upper thoracic motor-complete SCI who have an implanted epidural stimulator. We demonstrated that eSCS can reduce the elevation in blood pressure and prevent DARS-induced AD. The blood pressure variability analysis indicated that eSCS potentially reduced vascular sympathetic nervous system activity during DARS, compared to without eSCS. This case series provides evidence to support the use of eSCS to prevent AD episodes during routine bowel procedures, improving the quality of life for individuals with SCI and potentially reducing cardiovascular risks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.