Evidence map›Paper›PMID 37109203›Full record

ArticleJournal of clinical medicine2023

Effect of Selenium Deficiency on the Development of Overt Hepatic Encephalopathy in Patients with Chronic Liver Disease.

Yuki Nakahata, Tatsunori Hanai, Takao Miwa, Toshihide Maeda, Kenji Imai, Atsushi Suetsugu, Koji Takai, Masahito Shimizu

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yuki NakahataDepartment of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine, Gifu 5011194, Japan.ORCID 0000-0003-3593-413X
Tatsunori HanaiDepartment of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine, Gifu 5011194, Japan.
Takao MiwaDepartment of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine, Gifu 5011194, Japan.ORCID 0000-0002-6373-260X
Toshihide MaedaDepartment of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine, Gifu 5011194, Japan.
Kenji ImaiDepartment of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine, Gifu 5011194, Japan.
Atsushi SuetsuguDepartment of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine, Gifu 5011194, Japan.
Koji TakaiDepartment of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine, Gifu 5011194, Japan.
Masahito ShimizuDepartment of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine, Gifu 5011194, Japan.ORCID 0000-0002-1151-2058
Gifu University · JPAsahi University · JPGifu University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selenium is an essential trace element to maintain good health. This retrospective study investigated the prevalence of selenium deficiency and its effect on overt hepatic encephalopathy (OHE) in patients with chronic liver disease (CLD). Patients who underwent serum selenium level measurement between January 2021 and April 2022 were enrolled. The factors associated with selenium deficiency (≤10 µg/dL) and the association between selenium deficiency and OHE were analyzed. Among 98 eligible patients, 24% were observed to have selenium deficiency, with a median serum selenium level of 11.8 µg/dL. The serum selenium levels were significantly lower in patients with cirrhosis than in those with chronic hepatitis (10.9 µg/dL vs. 12.4 µg/dL;

Indexed as

fibrosishepatic encephalopathyseleniumselenoproteintrace element

Identifiers

PMID37109203
PMCPMC10143189
OpenAlexW4365513090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.