Evidence map›Paper›PMID 37109192›Full record

ArticleJournal of clinical medicine2023

Reoperation in Chiari-1 Malformations.

Giuseppe Talamonti, Marco Picano, Maria Fragale, Eleonora Marcati, Giulia Meccariello, Davide Boeris, Marco Cenzato

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. The role of tonsillar manipulation in posterior fossa decompression for Chiari I malformation: a 26-year institutional experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  2. Cervicomedullary CSF space obliteration as a risk factor of reoperation in Chiari malformation type I.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Giuseppe TalamontiDepartment of Neurosurgery, ASST Niguarda, 20162 Milan, Italy.
Marco PicanoDepartment of Neurosurgery, ASST Niguarda, 20162 Milan, Italy.
Maria FragaleDepartment of Neurosurgery, ASST Niguarda, 20162 Milan, Italy.
Eleonora MarcatiDepartment of Neurosurgery, ASST Niguarda, 20162 Milan, Italy.
Giulia MeccarielloDepartment of Neurosurgery, ASST Niguarda, 20162 Milan, Italy.
Davide BoerisDepartment of Neurosurgery, ASST Niguarda, 20162 Milan, Italy.
Marco CenzatoDepartment of Neurosurgery, ASST Niguarda, 20162 Milan, Italy.
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The issue of unsuccessful surgery for Chiari-1 malformation (CM-1), as well as its potential causes and possible solutions, remains poorly documented and studied. (2) Methods: From a retrospective review of a personal series of 98 patients undergoing treatment for CM-1 during the past 10 years, we created two study groups. Group 1: 8 patients (8.1%) requiring additional surgeries owing to postoperative complications (7 cerebrospinal fluid leakage, 1 extradural hematoma); 7 patients (7.1%) undergoing reoperations for failed decompression during the follow-up. Group 2: During the same period, we also managed 19 patients who had previously been operated on elsewhere: 8 patients who required adequate CM-1 treatment following extradural section of the filum terminale; 11 patients requiring reoperations for failed decompression. Failed decompression was managed by adequate osteodural decompression, which was associated with tonsillectomy (6 cases), subarachnoid exploration (8 cases), graft substitution (6 cases), and occipito-cervical fixation/revision (1 case). (3) Results: There was no mortality or surgical morbidity in Group 1. However, one patient's condition worsened due to untreatable syrinx. In Group 2, there were two cases of mortality, and surgical morbidity was represented by functional limitation and pain in the patient who needed revision of the occipitocervical fixation. Twenty patients improved (58.8%), 6 remained unchanged (32.3%), 1 worsened (2.9%) and 2 died (5.9%). (4) Conclusions: The rate of complications remains high in CM-1 treatment. Unfortunately, a certain rate of treatment failure is unavoidable, but it appears that a significant number of re-operations could have been avoided using proper indications and careful technique.

Indexed as

Chiari malformationcomplicationsCSF-leakforamen magnum decompressionreoperationsyringomyelia

Identifiers

PMID37109192
PMCPMC10142814
OpenAlexW4365514720

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.