Evidence map›Paper›PMID 37109147›Full record

ReviewJournal of clinical medicine2023

Alcohol Septal Ablation in Patients with Hypertrophic Obstructive Cardiomyopathy: A Contemporary Perspective.

Felice Gragnano, Francesco Pelliccia, Natale Guarnaccia, Giampaolo Niccoli, Salvatore De Rosa, Raffaele Piccolo, Elisabetta Moscarella, Enrico Fabris, Rocco Antonio Montone, Arturo Cesaro and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. A Road Less Traveled: Successful Alcohol Septal Ablation via an Aberrant Septal Coronary Artery in Hypertrophic Obstructive Cardiomyopathy.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 1 country.

Felice GragnanoDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 83043 Naples, Italy.ORCID 0000-0002-6943-278X
Francesco PellicciaDepartment of Cardiovascular Sciences, University Sapienza, 00185 Rome, Italy.ORCID 0000-0003-1260-1308
Natale GuarnacciaDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 83043 Naples, Italy.
Giampaolo NiccoliDepartment of Medicine and Surgery, University of Parma, 43121 Parma, Italy.
Salvatore De RosaDivision of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-5388-942X
Raffaele PiccoloDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80138 Naples, Italy.
Elisabetta MoscarellaDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 83043 Naples, Italy.
Enrico FabrisCardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-9458-0736
Rocco Antonio MontoneDepartment of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-6439-1018
Arturo CesaroDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 83043 Naples, Italy.ORCID 0000-0003-4435-1235
Italo PortoDipartimento CardioToracoVascolare, Ospedale Policlinico San Martino IRCCS, 16132 Genova, Italy.
Ciro IndolfiDivision of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-1241-6487
Gianfranco SinagraCardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), University of Trieste, 34127 Trieste, Italy.
Pasquale Perrone FilardiDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80138 Naples, Italy.
Giuseppe AndòDepartment of Clinical and Experimental Medicine, University of Messina, AOU Policlinic "G. Martino", 98122 Messina, Italy.ORCID 0000-0001-5552-6382
Paolo CalabròDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 83043 Naples, Italy.ORCID 0000-0002-5018-830X
Working Group of Interventional Cardiology of the Italian Society of Cardiology
University of Campania "Luigi Vanvitelli" · ITMagna Graecia University · ITUniversity of Naples Federico II · ITUniversity of Trieste · ITAgostino Gemelli University Polyclinic · ITOspedale Policlinico San Martino · ITSapienza University of Rome · ITUniversity of Messina · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol septal ablation is a minimally invasive procedure for the treatment of left ventricular outflow tract (LVOT) obstruction in patients with hypertrophic obstructive cardiomyopathy (HOCM) who remain symptomatic despite optimal medical therapy. The procedure causes a controlled myocardial infarction of the basal portion of the interventricular septum by the injection of absolute alcohol with the aim of reducing LVOT obstruction and improving the patient's hemodynamics and symptoms. Numerous observations have demonstrated the efficacy and safety of the procedure, making it a valid alternative to surgical myectomy. In particular, the success of alcohol septal ablation depends on appropriate patient selection and the experience of the institution where the procedure is performed. In this review, we summarize the current evidence on alcohol septal ablation and highlight the importance of a multidisciplinary approach involving a team of clinical and interventional cardiologists and cardiac surgeons with high expertise in the management of HOCM patients-the Cardiomyopathy Team.

Indexed as

alcohol septal ablationhypertrophic cardiomyopathymyectomy

Identifiers

PMID37109147
PMCPMC10142866
OpenAlexW4365146642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.