Evidence map›Paper›PMID 37109134›Full record

ReviewJournal of clinical medicine2023

Outcome of In-Hospital Cardiac Arrest among Patients with COVID-19: A Systematic Review and Meta-Analysis.

Dhan Bahadur Shrestha, Yub Raj Sedhai, Sagun Dawadi, Bishal Dhakal, Jurgen Shtembari, Karan Singh, Roshan Acharya, Soney Basnyat, Irfan Waheed, Mohammad Saud Khan and 6 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Dhan Bahadur ShresthaDepartment of Internal Medicine, Mount Sinai Hospital, Chicago, IL 60608, USA.ORCID 0000-0002-8121-083X
Yub Raj SedhaiDivision of Pulmonary Disease and Critical Care, University of Kentucky College of Medicine-Bowling Green Campus, E 1st Ave, Bowling Green, KY 42101, USA.ORCID 0000-0002-1755-5489
Sagun DawadiDepartment of Internal Medicine, Nepalese Army Institute of Health Sciences, Kathmandu 44600, Nepal.ORCID 0000-0001-9352-4847
Bishal DhakalDepartment of Internal Medicine, Nepalese Army Institute of Health Sciences, Kathmandu 44600, Nepal.ORCID 0000-0001-9432-5233
Jurgen ShtembariDepartment of Internal Medicine, Mount Sinai Hospital, Chicago, IL 60608, USA.ORCID 0000-0001-6071-4257
Karan SinghDivision of Pulmonary Disease and Critical Care, University of Kentucky College of Medicine-Bowling Green Campus, E 1st Ave, Bowling Green, KY 42101, USA.ORCID 0000-0002-1180-5926
Roshan AcharyaDivision of Pulmonary Disease and Critical Care Medicine, Virginia Tech Carilion School of Medicine, Roanoke, VA 24014, USA.ORCID 0000-0002-3794-2582
Soney BasnyatDepartment of Internal Medicine, University of Kentucky College of Medicine-Bowling Green Campus, E 1st Ave, Bowling Green, KY 42101, USA.
Irfan WaheedDivision of Pulmonary Disease and Critical Care, University of Kentucky College of Medicine-Bowling Green Campus, E 1st Ave, Bowling Green, KY 42101, USA.
Mohammad Saud KhanDivision of Cardiology, University of Kentucky College of Medicine-Bowling Green Campus, E 1st Ave, Bowling Green, KY 42101, USA.
Mohammed KazimuddinDivision of Cardiology, University of Kentucky College of Medicine-Bowling Green Campus, E 1st Ave, Bowling Green, KY 42101, USA.
Nimesh K PatelDepartment of Internal Medicine, Division of Cardiology, Virginia Commonwealth University School of Medicine, Richmond, VA 23219, USA.
Gautham KalahastyDepartment of Internal Medicine, Division of Cardiology, Virginia Commonwealth University School of Medicine, Richmond, VA 23219, USA.
Prashant Dattatraya BhaveDepartment of Internal Medicine, Division of Electrophysiology, Atrium Health Wake Forest Baptist Medical Center, Medical Center Boulevard, Winston-Salem, NC 27157, USA.ORCID 0000-0003-0664-7828
Patrick WhalenDepartment of Internal Medicine, Division of Electrophysiology, Atrium Health Wake Forest Baptist Medical Center, Medical Center Boulevard, Winston-Salem, NC 27157, USA.
Ghanshyam ShanthaDepartment of Internal Medicine, Division of Electrophysiology, Atrium Health Wake Forest Baptist Medical Center, Medical Center Boulevard, Winston-Salem, NC 27157, USA.ORCID 0000-0003-0939-140X
University of Kentucky · USAtrium Health Wake Forest Baptist · USMount Sinai Hospital · USNepalese Army Institute of Health Services · NPVirginia Commonwealth University · USCarilion Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOutcomes following in-hospital cardiac arrest (IHCA) in patients with COVID-19 have been reported by several small single-institutional studies; however, there are no large studies contrasting COVID-19 IHCA with non-COVID-19 IHCA. The objective of this study was to compare the outcomes following IHCA between COVID-19 and non-COVID-19 patients.

methodsWe searched databases using predefined search terms and appropriate Boolean operators. All the relevant articles published till August 2022 were included in the analyses. The systematic review and meta-analysis were conducted as per Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. An odds ratio with a 95% confidence interval (CI) was used to measure effects.

resultsAmong 855 studies screened, 6 studies with 27,453 IHCA patients (63.84% male) with COVID-19 and 20,766 (59.7% male) without COVID-19 were included in the analysis. IHCA among patients with COVID-19 has lower odds of achieving return of spontaneous circulation (ROSC) (OR: 0.66, 95% CI: 0.62-0.70). Similarly, patients with COVID-19 have higher odds of 30-day mortality following IHCA (OR: 2.26, 95% CI: 2.08-2.45) and have 45% lower odds of cardiac arrest because of a shockable rhythm (OR: 0.55, 95% CI: 0.50-0.60) (9.59% vs. 16.39%). COVID-19 patients less commonly underwent targeted temperature management (TTM) or coronary angiography; however, they were more commonly intubated and on vasopressor therapy as compared to patients who did not have a COVID-19 infection.

conclusionsThis meta-analysis showed that IHCA with COVID-19 has a higher mortality and lower rates of ROSC compared with non-COVID-19 IHCA. COVID-19 is an independent risk factor for poor outcomes in IHCA patients.

Indexed as

COVID-19in-hospital cardiac arrestmortality

Identifiers

PMID37109134
PMCPMC10144838
OpenAlexW4363674304

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.