Evidence map›Paper›PMID 37109121›Full record

ArticleJournal of clinical medicine2023

The Efficacy of Flogofilm

Biagio Barone, Benito Fabio Mirto, Alfonso Falcone, Francesco Del Giudice, Achille Aveta, Luigi Napolitano, Dario Del Biondo, Matteo Ferro, Gian Maria Busetto, Celeste Manfredi and 12 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. The Role of ButirprostMedicina (Kaunas, Lithuania) · 2025
    Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Prostate and urinary microbiomes in prostate cancer development: focus onFrontiers in cellular and infection microbiology · 2025
    Review
  8. Rare case of urinary tract infection caused byLe infezioni in medicina · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 7 institutions in 2 countries.

Biagio BaroneDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0003-4884-132X
Benito Fabio MirtoDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.
Alfonso FalconeDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.
Francesco Del GiudiceDepartment of Maternal Infant and Urologic Sciences, Policlinico Umberto I Hospital, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0003-3865-5988
Achille AvetaDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0001-8470-1995
Luigi NapolitanoDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.
Dario Del BiondoDepartment of Urology, Ospedale del Mare, ASL NA1 Centro, 80147 Naples, Italy.
Matteo FerroDepartment of Urology, European Institute of Oncology (IEO) IRCCS, 20141 Milan, Italy.ORCID 0000-0002-9250-7858
Gian Maria BusettoDepartment of Urology and Organ Transplantation, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-7291-0316
Celeste ManfrediUrology Unit, Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.ORCID 0000-0002-9706-8516
Daniela TerraccianoDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-4296-429X
Raffaele GambardellaUnit of Urology, ASL NA1 Centro, 80145 Naples, Italy.
Savio Domenico PandolfoDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.
Francesco TramaDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.
Ciro De LucaDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.
Raffaele MartinoDepartment of Urology, Ospedale del Mare, ASL NA1 Centro, 80147 Naples, Italy.
Federico CaponeDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.
Gaetano GiampagliaDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.
Enrico SicignanoDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0003-2725-8530
Octavian Sabin TataruDepartment of Simulation Applied in Medicine, The Institution Organizing University Doctoral Studies (I.O.S.U.D.), George Emil Palade University of Medicine, Pharmacy, Sciences, and Technology from Târgu Mureș, 540142 Târgu Mureș, Romania.ORCID 0000-0001-7057-7815
Giuseppe LucarelliUrology, Andrology and Kidney Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0001-7807-1229
Felice CrocettoDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0002-4315-7660
University of Naples Federico II · ITPoliclinico Umberto I · ITUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · ROUniversity of Bari Aldo Moro · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Foggia · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBacterial prostatitis (BP) is a common prostatic infection characterized by a bimodal distribution in young and older men, with a prevalence between 5-10% among all cases of prostatitis and a high impact on quality of life. Although the management of bacterial prostatitis involves the use of appropriate spectrum antibiotics, which represent the first choice of treatment, a multimodal approach encompassing antibiotics and nutraceutical products in order to improve the efficacy of chosen antimicrobial regimen is often required.

objectiveTo evaluate the efficacy of Flogofilm

methodsPatients diagnosed with prostatitis (positivity to Meares-Stamey Test and symptoms duration > 3 months) at the University of Naples "Federico II", Italy, from July 2021 to December 2021, were included in this study. All patients underwent bacterial cultures and trans-rectal ultrasounds. Patients were randomized into two groups (A and B) receiving antibiotic alone or an association of antibiotics plus Flogofilm

resultsA total of 96 (Group A = 47, Group B = 49) patients concluded the study protocol. The mean age was comparable, with a mean age of 34.62 ± 9.04 years for Group A and 35.29 ± 10.32 years for Group B (

conclusionsFlogofilm

Indexed as

chronic prostatitisFlogofilm®fluoroquinolonesIPSSNIH-CPSI

Identifiers

PMID37109121
PMCPMC10142953
OpenAlexW4362733608

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.