ArticleJournal of personalized medicine2023
Mediation Effects of Social Cognition on the Relationship between Neurocognition and Social Functioning in Major Depressive Disorder and Schizophrenia Spectrum Disorders.
Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Social Functioning Interventions in Psychosis: A Systematic Review.Clinical psychology & psychotherapyPooled it
- International perspective on social cognition in schizophrenia: current stage and the next steps.European psychiatry : the journal of the Association of European Psychiatrists · 2025Review
- Clinical subtypes of schizophrenia based on the discrepancies between objective performance on social cognition tasks and subjective difficulties in social cognition.Schizophrenia (Heidelberg, Germany) · 2024Article
- Negative symptoms and social cognition as mediators of the relationship between neurocognition and functional outcome in schizophrenia.Frontiers in psychiatry · 2024Article
- Deficits in Key Brain Network for Social Interaction in Individuals with Schizophrenia.Brain sciences · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundIn schizophrenia spectrum disorders (SSD), social cognition mediates the relationship between neurocognition and social functioning. Although people with major depressive disorder (MDD) also exhibit cognitive impairments, which are often prolonged, little is known about the role of social cognition in MDD.
methodsUsing data obtained through an internet survey, 210 patients with SSD or MDD were selected using propensity score matching based on their demographics and illness duration. Social cognition, neurocognition, and social functioning were evaluated using the Self-Assessment of Social Cognition Impairments, Perceived Deficits Questionnaire, and Social Functioning Scale, respectively. The mediation effects of social cognition on the relationship between neurocognition and social functioning were examined in each group. Invariances of the mediation model across the two groups were then analyzed.
resultsThe SSD and MDD groups had mean ages of 44.49 and 45.35 years, contained 42.0% and 42.8% women, and had mean illness durations of 10.76 and 10.45 years, respectively. In both groups, social cognition had significant mediation effects. Configural, measurement, and structural invariances across the groups were established.
conclusionThe role of social cognition in patients with MDD was similar to that in SSD. Social cognition could be a common endophenotype for various psychiatric disorders.
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