Evidence map›Paper›PMID 37108980›Full record

ArticleJournal of personalized medicine2023

LIFEHOUSE's Functional Nutrition Examination (Physical Exam, Anthropometrics, and Selected Biomarkers) Informs Personalized Wellness Interventions.

Michael Stone, Dan Lukaczer, Christopher R D'Adamo, Nicole Dotson, Andrey Volkov, Deanna Minich, Dina Metti, Michelle Leary, Monique Class, Malisa Carullo and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Michael StoneOffice of Personalized Health and Well-Being, Medical College of Georgia, AU/UGA Medical Partnership, Athens, GA 30606, USA.
Dan LukaczerInstitute for Functional Medicine, Federal Way, WA 98003, USA.
Christopher R D'AdamoInstitute for Functional Medicine, Federal Way, WA 98003, USA.ORCID 0000-0002-2415-8158
Nicole DotsonInstitute for Functional Medicine, Federal Way, WA 98003, USA.
Andrey VolkovBennett Data Sciences, San Diego, CA 92107, USA.
Deanna MinichInstitute for Functional Medicine, Federal Way, WA 98003, USA.ORCID 0000-0002-1103-8982
Dina MettiSwedish Medical Group, Seattle, WA 98122, USA.
Michelle LearyVida Integrated Health, Seattle, WA 98112, USA.
Monique ClassInstitute for Functional Medicine, Federal Way, WA 98003, USA.
Malisa CarulloMetagenics, Inc., Aliso Viejo, CA 92656, USA.
Erik LundquistPersonalized Lifestyle Medicine Center, Aliso Viejo, CA 92656, USA.
Brent EckMetagenics, Inc., Aliso Viejo, CA 92656, USA.
Jose OrdovasJean Meyer USDA Human Nutrition Center on Aging, Tufts University, Boston, MA 02111, USA.
Joseph LambPersonalized Lifestyle Medicine Center, Gig Harbor, WA 98332, USA.ORCID 0000-0003-1372-0077
Jeffrey BlandPersonalized Lifestyle Medicine Institute, Bainbridge Island, WA 98110, USA.
Psychogenics (United States) · USBennett Aerospace (United States) · USStamford Hospital · USSwedish Medical Center · USTufts University · USUniversity of Maryland, Baltimore · USUniversity of Western States · USVidant Health · US

Funding

Metagenics, Inc 999
6 · The paper itself

Abstract

Each individual has a unique and interacting set of genetic, lifestyle, and environmental factors that are reflected in their physical exam and laboratory biomarkers and significantly impact their experience of health. Patterns of nutrient deficiency signs and biomarker levels below health-promoting thresholds have been identified in national nutrition surveys. However, identifying these patterns remains a challenge in clinical medicine for many reasons, including clinician training and education, clinical time restraints, and the belief that these signs are both rare and recognizable only in cases of severe nutritional deficiencies. With an increased interest in prevention and limited resources for comprehensive diagnostic evaluations, a functional nutrition evaluation may augment patient-centered screening evaluations and personalized wellness programs. During LIFEHOUSE, we have documented physical exam, anthropometric, and biomarker findings that may increase the recognition of these wellness-challenging patterns in a population of 369 adult employees working in two occupational areas: administrative/sales and manufacturing/warehouse. Distinct and significant physical exam differences and constellations of biomarker abnormalities were identified. We present these patterns of physical exam findings, anthropometrics, and advanced biomarkers to assist clinicians in diagnostic and therapeutic interventions that may stem the loss of function that precedes the development of the non-communicable chronic diseases of aging.

Indexed as

biomarkersfunctional medicineLIFEHOUSE‘N-of-1’ trialsnutrient deficiencynutrient insufficiencynutrientspattern recognitionpersonalized lifestyle medicinephysical examination

Identifiers

PMID37108980
PMCPMC10145881
OpenAlexW4361290987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.