Evidence map›Paper›PMID 37108853›Full record

ArticleJournal of fungi (Basel, Switzerland)2023

COVID-19 Associated Pulmonary Aspergillosis in Patients on Extracorporeal Membrane Oxygenation Treatment-A Retrospective Study.

Ali Nuh, Newara Ramadan, Lisa Nwankwo, Jackie Donovan, Brijesh Patel, Anand Shah, Sujal R Desai, Darius Armstrong-James

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ali NuhLaboratory Medicine, Department of Microbiology, Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London SW3 6NP, UK.ORCID 0000-0002-3738-8833
Newara RamadanLaboratory Medicine, Department of Microbiology, Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London SW3 6NP, UK.ORCID 0000-0003-3628-559X
Lisa NwankwoPharmacy Department, Royal Brompton Hospital, Guy's and St. Thomas' NHS Foundation Trust, London SW3 6NP, UK.ORCID 0000-0001-9146-2873
Jackie DonovanDepartment of Chemical Pathology, Royal Brompton Hospital, Guy's and St. Thomas' NHS Foundation Trust, London SW3 6NP, UK.
Brijesh PatelDivision of Anaesthetics, Pain Medicine, and Intensive Care, Department of Surgery and Cancer, Centre for Haematology, Department of Immunology and Inflammation, and 5 National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.
Anand ShahMRC Centre of Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London SW7 2AZ, UK.
Sujal R DesaiImaging Department, Royal Brompton Hospital, Guy's and St. Thomas' NHS Foundation Trust, London SW3 6NP, UK.ORCID 0000-0002-5237-3613
Darius Armstrong-JamesLaboratory Medicine, Department of Microbiology, Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London SW3 6NP, UK.
Guy's and St Thomas' NHS Foundation Trust · GBImperial College London · GB

Funding

Medical Research Council MR/R015600/1Medical Research Council MR/T005572/1Medical Research Council MR/V037315/1Wellcome Trust
6 · The paper itself

Abstract

backgroundThe incidence and outcome of pulmonary aspergillosis in coronavirus disease (COVID-19) patients on extracorporeal membrane oxygenation (ECMO) are unknown and have not been fully addressed. We investigated the incidence, risk factors and outcome of pulmonary aspergillosis in COVID-19 ECMO patients. In addition, the diagnostic utility of bronchoalveolar lavage fluid and CT scans in this setting were assessed.

methodsWe conducted a retrospective study on incidence and outcome of pulmonary aspergillosis in COVID-19 ECMO patients by reviewing clinical, radiological, and mycological evidence. These patients were admitted to a tertiary cardiothoracic centre during the early COVID-19 surge between March 2020 and January 2021. Results and measurements: The study included 88 predominantly male COVID-19 ECMO patients with a median age and a BMI of 48 years and 32 kg/m

conclusionsIn COVID-19 ECMO patients, pulmonary aspergillosis incidence was 10% and associated with very high mortality. Our results support the role of BALF in the diagnosis of pulmonary aspergillosis in COVID-19 ECMO patients. However, the diagnostic utility of BDG, serum GM, and CT scans is unclear.

Indexed as

Aspergillus speciesCOVID-19ECMOincidenceoutcomepulmonary aspergillosis

Identifiers

PMID37108853
PMCPMC10146650
OpenAlexW4360863105

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.