A Functional Yeast-Based Screen Identifies the Host Microtubule Cytoskeleton as a Target of Numerous

Carolin Wevers, Mona Höhler, Abel R Alcázar-Román, Johannes H Hegemann, Ursula Fleig

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.4field-weighted citation impact, top 41% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

Direct targeting of host microtubule and actin cytoskeletons by a chlamydial pathogenic effector protein.Journal of cell science · 2024
Article
Unravelling bacterial virulence factors in yeast: From identification to the elucidation of their mechanisms of action.Archives of microbiology · 2024
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Carolin WeversEukaryotic Microbiology, Institute of Functional Microbial Genomics, Heinrich-Heine-University, 40225 Düsseldorf, Germany.

Mona HöhlerEukaryotic Microbiology, Institute of Functional Microbial Genomics, Heinrich-Heine-University, 40225 Düsseldorf, Germany.ORCID 0000-0002-3573-953X

Abel R Alcázar-RománEukaryotic Microbiology, Institute of Functional Microbial Genomics, Heinrich-Heine-University, 40225 Düsseldorf, Germany.

Johannes H HegemannInstitute of Functional Microbial Genomics, Heinrich-Heine-University, 40225 Düsseldorf, Germany.

Ursula FleigEukaryotic Microbiology, Institute of Functional Microbial Genomics, Heinrich-Heine-University, 40225 Düsseldorf, Germany.ORCID 0000-0002-0270-0970

Heinrich Heine University Düsseldorf · DE

Funding

Deutsche Forschungsgemeinschaft FL 168/5-1Deutsche Forschungsgemeinschaft HE 1383/13-1Jürgen Manchot Stiffung MH

6 · The paper itself

Abstract

Bacterial pathogens have evolved intricate ways to manipulate the host to support infection. Here, we systematically assessed the importance of the microtubule cytoskeleton for infection by

Indexed as

Chlamydophila pneumoniaeSchizosaccharomycesChlamydia trachomatisCytoskeletonHumansMicrotubule-Associated ProteinsMicrotubulesSaccharomyces cerevisiaeMicrotubule-Associated ProteinsbacteriaChlamydia pneumoniaeeffector proteinsMAPsmicrotubule cytoskeletonpathogenSchizosaccharomyces pombescreenyeast

Identifiers

PMID37108781

DOI10.3390/ijms24087618

PMCPMC10142024

OpenAlexW4366775289

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.