Evidence map›Paper›PMID 37108774›Full record

ArticleInternational journal of molecular sciences2023

Enzymatic Synthesis of a Novel Coumarin Aminophosphonates: Antibacterial Effects and Oxidative Stress Modulation on Selected

Dominik Koszelewski, Paweł Kowalczyk, Anna Brodzka, Anastasiia Hrunyk, Karol Kramkowski, Ryszard Ostaszewski

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. SnClRSC advances · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Coumarin: A natural solution for alleviating inflammatory disorders.Current research in pharmacology and drug discovery · 2024
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Dominik KoszelewskiInstitute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
Paweł KowalczykDepartment of Animal Nutrition, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland.ORCID 0000-0003-4025-3750
Anna BrodzkaInstitute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.ORCID 0000-0002-6659-0758
Anastasiia HrunykInstitute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
Karol KramkowskiDepartment of Physical Chemistry, Medical University of Bialystok, Kilińskiego 1 Str., 15-089 Białystok, Poland.
Ryszard OstaszewskiInstitute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.ORCID 0000-0002-3032-196X
Institute of Organic Chemistry · PLKielanowski Institute of Animal Physiology and Nutrition · PLMedical University of Białystok · PL

Funding

Medical University of Białystok Grant of National Science Center Opus 22 Nr 2021/43/B/NZ7/01903National Science Center, Poland project OPUS 2019/33/B/ST4/01118; SUB1/NN/22/001/2201; B.SUB.23.359; SUB/2/NN/22/001/2201
6 · The paper itself

Abstract

The objective of the present study was to evaluate the synergistic effect of two important pharmacophores, coumarin and α-amino dimethyl phosphonate moieties, on antimicrobial activity toward selected LPS-varied

Indexed as

Anti-Infective AgentsOrganophosphonatesAnti-Bacterial AgentsCoumarinsEscherichia coliMicrobial Sensitivity TestsOxidative StressPhosphitesStructure-Activity RelationshipAnti-Bacterial AgentsAnti-Infective AgentsCoumarinsdimethyl hydrogen phosphiteOrganophosphonatesPhosphitesaminophosphonatesantimicrobial activitycoumarinsE. coli cellsenzymatic catalytic promiscuityKabachnik-Fields reactionlipasesMICmulticomponent reaction

Identifiers

PMID37108774
PMCPMC10146307
OpenAlexW4366690865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.