Evidence map›Paper›PMID 37108725›Full record

ReviewInternational journal of molecular sciences2023

Recent Advances in Antimicrobial Peptide Hydrogels.

Aryanna Copling, Maxwell Akantibila, Raaha Kumaresan, Gilbert Fleischer, Dennise Cortes, Rahul S Tripathi, Valerie J Carabetta, Sebastián L Vega

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Exploring New Horizons in Wound Healing: A Comprehensive Analysis.Recent advances in inflammation & allergy drug discovery · 2026
    Review
  7. Antimicrobial Hydrogel for Diabetic Wound Treatment.International journal of nanomedicine · 2026
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Current protein & peptide science · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Special Issue "Antimicrobial Biomaterials: Recent Progress".International journal of molecular sciences · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aryanna CoplingDepartment of Molecular & Cellular Biosciences, Rowan University, Glassboro, NJ 08028, USA.
Maxwell AkantibilaDepartment of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ 08103, USA.
Raaha KumaresanDepartment of Biomedical Engineering, Rowan University, Glassboro, NJ 08028, USA.
Gilbert FleischerDepartment of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ 08103, USA.
Dennise CortesDepartment of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ 08103, USA.
Rahul S TripathiDepartment of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ 08103, USA.
Valerie J CarabettaDepartment of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ 08103, USA.ORCID 0000-0002-2211-0556
Sebastián L VegaDepartment of Biomedical Engineering, Rowan University, Glassboro, NJ 08028, USA.ORCID 0000-0002-7669-1552

Funding

U-Rise at Rowan UniversityT34GM136492 · NIGMS · ROWAN UNIVERSITY · PI KECK, THOMAS MCGOWAN, NUCCI, NATHANIEL V · 2021 to 2025
$2.0M
NIGMS NIH HHS Biomedical Sciences departmental awardNIGMS NIH HHS T34 GM136492NIGMS NIH HHS T34GM136492
6 · The paper itself

Abstract

Advances in the number and type of available biomaterials have improved medical devices such as catheters, stents, pacemakers, prosthetic joints, and orthopedic devices. The introduction of a foreign material into the body comes with a risk of microbial colonization and subsequent infection. Infections of surgically implanted devices often lead to device failure, which leads to increased patient morbidity and mortality. The overuse and improper use of antimicrobials has led to an alarming rise and spread of drug-resistant infections. To overcome the problem of drug-resistant infections, novel antimicrobial biomaterials are increasingly being researched and developed. Hydrogels are a class of 3D biomaterials consisting of a hydrated polymer network with tunable functionality. As hydrogels are customizable, many different antimicrobial agents, such as inorganic molecules, metals, and antibiotics have been incorporated or tethered to them. Due to the increased prevalence of antibiotic resistance, antimicrobial peptides (AMPs) are being increasingly explored as alternative agents. AMP-tethered hydrogels are being increasingly examined for antimicrobial properties and practical applications, such as wound-healing. Here, we provide a recent update, from the last 5 years of innovations and discoveries made in the development of photopolymerizable, self-assembling, and AMP-releasing hydrogels.

Indexed as

Anti-Infective AgentsAntimicrobial PeptidesAnti-Bacterial AgentsBiocompatible MaterialsHumansHydrogelsAnti-Bacterial AgentsAnti-Infective AgentsAntimicrobial PeptidesBiocompatible MaterialsHydrogelsAMP-releasingantibiotic resistanceantimicrobial peptidebiofilmclick chemistryhydrogelphotopolymerizationself-assembling

Identifiers

PMID37108725
PMCPMC10139150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.