Evidence map›Paper›PMID 37108689›Full record

ArticleInternational journal of molecular sciences2023

Cannabis Use and Endocannabinoid Receptor Genes: A Pilot Study on Their Interaction on Brain Activity in First-Episode Psychosis.

Maitane Oscoz-Irurozqui, Carmen Almodóvar-Payá, Maria Guardiola-Ripoll, Amalia Guerrero-Pedraza, Noemí Hostalet, Raymond Salvador, Maria Isabel Carrión, Teresa Maristany, Edith Pomarol-Clotet, Mar Fatjó-Vilas

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Maitane Oscoz-IrurozquiFIDMAG Germanes Hospitalàries Research Foundation, Av Jordà 8, 08035 Barcelona, Spain.
Carmen Almodóvar-PayáFIDMAG Germanes Hospitalàries Research Foundation, Av Jordà 8, 08035 Barcelona, Spain.
Maria Guardiola-RipollFIDMAG Germanes Hospitalàries Research Foundation, Av Jordà 8, 08035 Barcelona, Spain.ORCID 0000-0001-6949-5687
Amalia Guerrero-PedrazaFIDMAG Germanes Hospitalàries Research Foundation, Av Jordà 8, 08035 Barcelona, Spain.ORCID 0000-0001-7567-9407
Noemí HostaletFIDMAG Germanes Hospitalàries Research Foundation, Av Jordà 8, 08035 Barcelona, Spain.
Raymond SalvadorFIDMAG Germanes Hospitalàries Research Foundation, Av Jordà 8, 08035 Barcelona, Spain.
Maria Isabel CarriónHospital Sant Rafael, Passeig de la Vall d'Hebron, 107, 08035 Barcelona, Spain.
Teresa MaristanyDiagnostic Imaging Department, Hospital Sant Joan de Déu Research Foundation, Passeig de Sant Joan de Déu, 2, 08950 Esplugues de Llobregat, Barcelona, Spain.
Edith Pomarol-ClotetFIDMAG Germanes Hospitalàries Research Foundation, Av Jordà 8, 08035 Barcelona, Spain.
Mar Fatjó-VilasFIDMAG Germanes Hospitalàries Research Foundation, Av Jordà 8, 08035 Barcelona, Spain.ORCID 0000-0001-9963-6241
Instituto de Salud Carlos III · ESHospital Mare de Déu de la Mercè · ESHospital Universitario San Rafael · ESOsakidetza · ESSant Joan de Déu Research Foundation · ES

Funding

Instituto de Salud Carlos III PI14/01151, PI15/01420, PI18/01535, FI19/0352, FI21/00093, CP20/00072
6 · The paper itself

Abstract

The role of both cannabis use and genetic background has been shown in the risk for psychosis. However, the effect of the interplay between cannabis and variability at the endocannabinoid receptor genes on the neurobiological underpinnings of psychosis remains inconclusive. Through a case-only design, including patients with a first-episode of psychosis (n = 40) classified as cannabis users (50%) and non-users (50%), we aimed to evaluate the interaction between cannabis use and common genetic variants at the endocannabinoid receptor genes on brain activity. Genetic variability was assessed by genotyping two Single Nucleotide Polymorphisms (SNP) at the cannabinoid receptor type 1 gene (

Indexed as

CannabisPsychotic DisordersBrainEndocannabinoidsHumansPilot ProjectsReceptors, CannabinoidEndocannabinoidsReceptors, Cannabinoidcannabinoid receptor genescannabis usefirst-episode of psychosisfMRI working memory

Identifiers

PMID37108689
PMCPMC10142622
OpenAlexW4366550693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.