Evidence map›Paper›PMID 37108644›Full record

ReviewInternational journal of molecular sciences2023

Ribosome Specialization in Protozoa Parasites.

Cristian Camilo Rodríguez-Almonacid, Morgana K Kellogg, Andrey L Karamyshev, Zemfira N Karamysheva

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Non-coding RNAs as emerging players inFrontiers in cellular and infection microbiology · 2025
    Article
  8. Article
  9. Molecular Mechanisms of Drug Resistance inPathogens (Basel, Switzerland) · 2024
    Review
  10. Article
  11. Immune priming modulatesFrontiers in immunology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cristian Camilo Rodríguez-AlmonacidDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
Morgana K KelloggDepartment of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.ORCID 0000-0003-2286-235X
Andrey L KaramyshevDepartment of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.ORCID 0000-0001-9645-1655
Zemfira N KaramyshevaDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-1589-0216

Funding

Ribosome remodeling as a mechanism of translational control during stressR15GM146171 · NIGMS · TEXAS TECH UNIVERSITY · PI SALAZAR-BRAVO, JORGE · 2022 to 2023
$559k
NIGMS NIH HHS R15 GM146171NIGMS NIH HHS R15GM146171
6 · The paper itself

Abstract

Ribosomes, in general, are viewed as constitutive macromolecular machines where protein synthesis takes place; however, this view has been recently challenged, supporting the hypothesis of ribosome specialization and opening a completely new field of research. Recent studies have demonstrated that ribosomes are heterogenous in their nature and can provide another layer of gene expression control by regulating translation. Heterogeneities in ribosomal RNA and ribosomal proteins that compose them favor the selective translation of different sub-pools of mRNAs and functional specialization. In recent years, the heterogeneity and specialization of ribosomes have been widely reported in different eukaryotic study models; however, few reports on this topic have been made on protozoa and even less on protozoa parasites of medical importance. This review analyzes heterogeneities of ribosomes in protozoa parasites highlighting the specialization in their functions and their importance in parasitism, in the transition between stages in their life cycle, in the change of host and in response to environmental conditions.

Indexed as

ParasitesAnimalsProtein BiosynthesisRibosomal ProteinsRibosomesRNA, RibosomalRibosomal ProteinsRNA, RibosomalApicomplexamRNA translationribosomal proteinribosomal RNAribosome heterogeneityribosome specializationtranslational controlTrypanosomatidae

Identifiers

PMID37108644
PMCPMC10138883

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.