Evidence map›Paper›PMID 37108621›Full record

ReviewInternational journal of molecular sciences2023

Heat Shock Proteins in Tooth Development and Injury Repair.

Shuling Guo, Haosun Yang, Jiacheng Liu, Zhaosong Meng, Lei Sui

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Chaperonin in health and disease.Molecular biomedicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuling GuoSchool of Stomatology, Tianjin Medical University, Tianjin 300014, China.
Haosun YangSchool of Stomatology, Tianjin Medical University, Tianjin 300014, China.
Jiacheng LiuSchool of Stomatology, Tianjin Medical University, Tianjin 300014, China.
Zhaosong MengSchool of Stomatology, Tianjin Medical University, Tianjin 300014, China.ORCID 0000-0002-8977-8446
Lei SuiSchool of Stomatology, Tianjin Medical University, Tianjin 300014, China.

Funding

National Natural Science Foundation of China 81700927Tianjin Municipal Science and Technology Commission 21JCQNJC01190
6 · The paper itself

Abstract

Heat shock proteins (HSPs) are a class of molecular chaperones with expression increased in response to heat or other stresses. HSPs regulate cell homeostasis by modulating the folding and maturation of intracellular proteins. Tooth development is a complex process that involves many cell activities. During tooth preparation or trauma, teeth can be damaged. The damaged teeth start their repair process by remineralizing and regenerating tissue. During tooth development and injury repair, different HSPs have different expression patterns and play a special role in odontoblast differentiation and ameloblast secretion by mediating signaling pathways or participating in protein transport. This review explores the expression patterns and potential mechanisms of HSPs, particularly HSP25, HSP60 and HSP70, in tooth development and injury repair.

Indexed as

Heat-Shock ProteinsMolecular ChaperonesHSP70 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsOdontogenesisHeat-Shock ProteinsHSP70 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsMolecular Chaperonesheat shock proteinsignaling pathwaytooth developmenttooth injury repair

Identifiers

PMID37108621
PMCPMC10138928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.