Evidence map›Paper›PMID 37108540›Full record

ArticleInternational journal of molecular sciences2023

Characterization and In Vivo Assay of Allantoin-Enriched Pectin Hydrogel for the Treatment of Skin Wounds.

Rosa Alicia Saucedo-Acuña, Karen Zulema Meza-Valle, Juan Carlos Cuevas-González, Elsa Gabriela Ordoñez-Casanova, Manuel Iván Castellanos-García, Erasto Armando Zaragoza-Contreras, Genaro Federico Tamayo-Pérez

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rosa Alicia Saucedo-AcuñaInstitute of Biomedical Sciences, Autonomous University of Ciudad Juarez, Av. Benjamín Franklin No. 4650, Zona Pronaf Condominio La Plata, Ciudad Juárez C.P. 32310, Mexico.ORCID 0000-0003-1051-7858
Karen Zulema Meza-ValleInstitute of Biomedical Sciences, Autonomous University of Ciudad Juarez, Av. Benjamín Franklin No. 4650, Zona Pronaf Condominio La Plata, Ciudad Juárez C.P. 32310, Mexico.
Juan Carlos Cuevas-GonzálezInstitute of Biomedical Sciences, Autonomous University of Ciudad Juarez, Av. Benjamín Franklin No. 4650, Zona Pronaf Condominio La Plata, Ciudad Juárez C.P. 32310, Mexico.
Elsa Gabriela Ordoñez-CasanovaInstitute of Engineering and Technology, Autonomous University of Ciudad Juarez, Av. del Charro y Henry Dunan s/n, Omega, Ciudad Juárez C.P. 32584, Mexico.
Manuel Iván Castellanos-GarcíaInstitute of Engineering and Technology, Autonomous University of Ciudad Juarez, Av. del Charro y Henry Dunan s/n, Omega, Ciudad Juárez C.P. 32584, Mexico.
Erasto Armando Zaragoza-ContrerasCentro de Investigación en Materiales Avanzados, S.C. Miguel de Cervantes No. 120, Complejo Industrial Chihuahua, Chihuahua C.P. 31136, Mexico.ORCID 0000-0003-3010-556X
Genaro Federico Tamayo-PérezJefatura de Investigación, Hospital Ángeles Ciudad Juárez, Av. Campos Eliseos 9371, Campos Elíseos, Ciudad Juárez C.P. 32472, Mexico.
Universidad Autónoma de Ciudad Juárez · MXCentro de Investigación en Materiales Avanzados · MXHospital Juárez de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work describes a liquid allantoin-enriched pectin hydrogel with hydrophilic behavior that is supported by the presence of functional groups related to healing efficacy. A topical study shows the effect of the hydrogel application on surgically induced skin wound healing in a rat model. Contact angle measurements confirm hydrophilic behavior (11.37°), while Fourier-transform infrared spectroscopy indicates the presence of functional groups related to the healing effectiveness (carboxylic acid and amine groups). Allantoin is distributed on the surface and inside the amorphous pectin hydrogel surrounded by a heterogeneous distribution of pores. This promotes wound drying with better interaction between the hydrogel and cells involved in the wound healing process. An experimental study with female

Indexed as

AllantoinHydrogelsAnimalsFemalePectinsRatsRats, WistarSkinAllantoinHydrogelsPectinsallantoinhydrogelpectinskin regenerationwound healing

Identifiers

PMID37108540
PMCPMC10138972
OpenAlexW4366091993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.