Evidence map›Paper›PMID 37108450›Full record

ArticleInternational journal of molecular sciences2023

Functional and Anatomical Outcomes of Anti-Vascular Endothelial Growth Factor Treatment for Exudative Age-Related Macular Degeneration with or without Obstructive Sleep Apnea.

Nan-Ni Chen, Chau-Yin Chen, Jin-Jhe Wang, Heng-Chiao Huang, Wei-Dar Chen, Ching-Lung Chen, Yao-Hsu Yang, Meng-Hung Lin, Ting-Yu Kuo, Chien-Hsiung Lai

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Nan-Ni ChenDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.ORCID 0000-0002-1577-4012
Chau-Yin ChenDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Jin-Jhe WangDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.ORCID 0000-0003-3996-1127
Heng-Chiao HuangDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.ORCID 0000-0002-9176-6823
Wei-Dar ChenDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.ORCID 0000-0002-4336-5099
Ching-Lung ChenDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Yao-Hsu YangCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Meng-Hung LinHealth Information and Epidemiology Laboratory, Chang Gung Memorial Hospital, Chiayi Branch, Chiayi 61363, Taiwan.ORCID 0000-0002-8594-3360
Ting-Yu KuoHealth Information and Epidemiology Laboratory, Chang Gung Memorial Hospital, Chiayi Branch, Chiayi 61363, Taiwan.
Chien-Hsiung LaiDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.ORCID 0000-0001-8334-4156
Chiayi Chang Gung Memorial Hospital · TWChung Hwa University of Medical Technology · TWChang Gung University · TWChang Gung University of Science and Technology · TW

Funding

Chiayi Chang Gung Memorial Hospital CGRPG6L0021
6 · The paper itself

Abstract

(1) To investigate the functional and anatomical outcomes of anti-vascular endothelial growth factor (anti-VEGF) treatment in patients with exudative age-related macular degeneration (AMD) with or without obstructive sleep apnea (OSA); (2) In total, 65 patients with AMD with or without OSA who received three consecutive doses of intravitreal anti-VEGF injections were enrolled. The primary outcomes-best-corrected visual acuity (BCVA) and central macular thickness (CMT)-were assessed at 1 and 3 months. Moreover, morphological changes observed through optical coherence tomography were analyzed; (3) In total, 15 of the 65 patients had OSA and were included in the OSA group; the remaining 50 patients were included in the non-OSA (control) group. At 1 and 3 months after treatment, BCVA and CMT had improved but did not differ significantly between the groups. More patients in the OSA group demonstrated subretinal fluid (SRF) resorption at 3 months after treatment than in the non-OSA group (

Indexed as

Macular DegenerationSleep Apnea, ObstructiveAngiogenesis InhibitorsHumansProspective StudiesRanibizumabTomography, Optical CoherenceTreatment OutcomeVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsAngiogenesis InhibitorsRanibizumabVascular Endothelial Growth Factor AVascular Endothelial Growth Factorsage-related macular degenerationanti-vascular endothelial growth factor treatmentobstructive sleep apnea

Identifiers

PMID37108450
PMCPMC10138351
OpenAlexW4365510040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.