Evidence map›Paper›PMID 37108367›Full record

ArticleInternational journal of molecular sciences2023

Immunophenotyping of Monocyte Migration Markers and Therapeutic Effects of Selenium on IL-6 and IL-1β Cytokine Axes of Blood Mononuclear Cells in Preoperative and Postoperative Coronary Artery Disease Patients.

Max Wacker, Anna Ball, Hans-Dietmar Beer, Ingo Schmitz, Katrin Borucki, Faranak Azizzadeh, Maximilian Scherner, George Awad, Jens Wippermann, Priya Veluswamy

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Molecular medicine reports · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Max WackerHeart Surgery Research, Department of Cardiothoracic Surgery, Otto-von-Guericke University Hospital, Leipziger Straße 44, 39120 Magdeburg, Germany.ORCID 0000-0003-0664-2613
Anna BallHeart Surgery Research, Department of Cardiothoracic Surgery, Otto-von-Guericke University Hospital, Leipziger Straße 44, 39120 Magdeburg, Germany.
Hans-Dietmar BeerDepartment of Dermatology, University Hospital Zurich, CH-8952 Schlieren, Switzerland.ORCID 0000-0002-8085-713X
Ingo SchmitzDepartment of Molecular Immunology, Medical Faculty of Ruhr-University Bochum, 44801 Bochum, Germany.ORCID 0000-0002-5360-0419
Katrin BoruckiInstitute of Clinical Chemistry and Pathobiochemistry, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Faranak AzizzadehHeart Surgery Research, Department of Cardiothoracic Surgery, Otto-von-Guericke University Hospital, Leipziger Straße 44, 39120 Magdeburg, Germany.
Maximilian SchernerHeart Surgery Research, Department of Cardiothoracic Surgery, Otto-von-Guericke University Hospital, Leipziger Straße 44, 39120 Magdeburg, Germany.
George AwadHeart Surgery Research, Department of Cardiothoracic Surgery, Otto-von-Guericke University Hospital, Leipziger Straße 44, 39120 Magdeburg, Germany.ORCID 0000-0002-4432-1733
Jens WippermannHeart Surgery Research, Department of Cardiothoracic Surgery, Otto-von-Guericke University Hospital, Leipziger Straße 44, 39120 Magdeburg, Germany.
Priya VeluswamyHeart Surgery Research, Department of Cardiothoracic Surgery, Otto-von-Guericke University Hospital, Leipziger Straße 44, 39120 Magdeburg, Germany.
University Hospital Leipzig · DEOtto-von-Guericke-Universität Magdeburg · DERuhr University Bochum · DEUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multivessel coronary artery disease (CAD) is characterized by underlying chronic vascular inflammation and occlusion in the coronary arteries, where these patients undergo coronary artery bypass grafting (CABG). Since post-cardiotomy inflammation is a well known phenomenon after CABG, attenuation of this inflammation is required to reduce perioperative morbidity and mortality. In this study, we aimed to phenotype circulating frequencies and intensities of monocyte subsets and monocyte migration markers, respectively, and to investigate the plasma level of inflammatory cytokines and chemokines between preoperative and postoperative CAD patients and later, to intervene the inflammation with sodium selenite. We found a higher amplitude of inflammation, postoperatively, in terms of CCR1

Indexed as

Coronary Artery DiseaseSeleniumCytokinesHumansImmunophenotypingInflammationInterleukin-1betaInterleukin-6MonocytesTumor Necrosis Factor-alphaCytokinesInterleukin-1betaInterleukin-6SeleniumTumor Necrosis Factor-alphacoronary artery diseasepost-cardiotomy syndromepro-inflammatory cytokines and monocytesselenium

Identifiers

PMID37108367
PMCPMC10139122
OpenAlexW4365515302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.